No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe.
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No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe. / Stieler, Kristin; Schindler, Sarah; Schlomm, Thorsten; Hohn, Oliver; Bannert, Norbert; Simon, Ronald; Minner, Sarah Jane Pauline; Schindler, Michael; Fischer, Nicole.
in: PLOS ONE, Jahrgang 6, Nr. 10, 10, 2011, S. 25592.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe.
AU - Stieler, Kristin
AU - Schindler, Sarah
AU - Schlomm, Thorsten
AU - Hohn, Oliver
AU - Bannert, Norbert
AU - Simon, Ronald
AU - Minner, Sarah Jane Pauline
AU - Schindler, Michael
AU - Fischer, Nicole
PY - 2011
Y1 - 2011
N2 - We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR. The controversial discussion about the virus being detected in PCA tissue, blood samples from patients suffering from chronic fatigue syndrome (CFS), as well as from a significant number of healthy controls prompted us to deepen our studies about detection of XMRV infection applying different detection methods (PCR, cocultivation and immunohistochemistry [IHC]).
AB - We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR. The controversial discussion about the virus being detected in PCA tissue, blood samples from patients suffering from chronic fatigue syndrome (CFS), as well as from a significant number of healthy controls prompted us to deepen our studies about detection of XMRV infection applying different detection methods (PCR, cocultivation and immunohistochemistry [IHC]).
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Middle Aged
KW - Europe
KW - Immunohistochemistry
KW - Cell Line, Tumor
KW - Coculture Techniques
KW - Case-Control Studies
KW - Polymerase Chain Reaction
KW - Cell Separation
KW - Leukocytes, Mononuclear/virology
KW - Lymphocyte Activation/immunology
KW - Prostate/pathology/virology
KW - Prostatic Neoplasms/blood/pathology/virology
KW - Retroviridae Infections/virology
KW - Viral Proteins/metabolism
KW - Virus Replication
KW - Xenotropic murine leukemia virus-related virus/genetics/isolation & purification/physiology
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Middle Aged
KW - Europe
KW - Immunohistochemistry
KW - Cell Line, Tumor
KW - Coculture Techniques
KW - Case-Control Studies
KW - Polymerase Chain Reaction
KW - Cell Separation
KW - Leukocytes, Mononuclear/virology
KW - Lymphocyte Activation/immunology
KW - Prostate/pathology/virology
KW - Prostatic Neoplasms/blood/pathology/virology
KW - Retroviridae Infections/virology
KW - Viral Proteins/metabolism
KW - Virus Replication
KW - Xenotropic murine leukemia virus-related virus/genetics/isolation & purification/physiology
U2 - 10.1371/journal.pone.0025592
DO - 10.1371/journal.pone.0025592
M3 - SCORING: Journal article
VL - 6
SP - 25592
JO - PLOS ONE
JF - PLOS ONE
SN - 1932-6203
IS - 10
M1 - 10
ER -