No correlation between neuroleptic-induced increase of beta-endorphin serum level and therapeutic efficacy in schizophrenia.

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No correlation between neuroleptic-induced increase of beta-endorphin serum level and therapeutic efficacy in schizophrenia. / Naber, Dieter; Nedopil, N; Eben, E.

In: BRIT J PSYCHIAT, Vol. 144, 1984, p. 651-653.

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@article{498a78be6b98464ba20b53782f339f24,
title = "No correlation between neuroleptic-induced increase of beta-endorphin serum level and therapeutic efficacy in schizophrenia.",
abstract = "In 23 acute, unmedicated, schizophrenic patients, psychotic behaviour and beta-endorphin serum level were measured before and during four weeks of neuroleptic therapy. Prior to drug treatment, beta-endorphin level of all patients was within the normal range. Neuroleptic therapy induced marked elevations of beta-endorphin in eight subjects; statistical analysis revealed a slight but significant increase for the whole group. This endocrine effect was not correlated with therapeutic efficacy of neuroleptic treatment.",
author = "Dieter Naber and N Nedopil and E Eben",
year = "1984",
language = "Deutsch",
volume = "144",
pages = "651--653",
journal = "BRIT J PSYCHIAT",
issn = "0007-1250",
publisher = "Royal College of Psychiatrists",

}

RIS

TY - JOUR

T1 - No correlation between neuroleptic-induced increase of beta-endorphin serum level and therapeutic efficacy in schizophrenia.

AU - Naber, Dieter

AU - Nedopil, N

AU - Eben, E

PY - 1984

Y1 - 1984

N2 - In 23 acute, unmedicated, schizophrenic patients, psychotic behaviour and beta-endorphin serum level were measured before and during four weeks of neuroleptic therapy. Prior to drug treatment, beta-endorphin level of all patients was within the normal range. Neuroleptic therapy induced marked elevations of beta-endorphin in eight subjects; statistical analysis revealed a slight but significant increase for the whole group. This endocrine effect was not correlated with therapeutic efficacy of neuroleptic treatment.

AB - In 23 acute, unmedicated, schizophrenic patients, psychotic behaviour and beta-endorphin serum level were measured before and during four weeks of neuroleptic therapy. Prior to drug treatment, beta-endorphin level of all patients was within the normal range. Neuroleptic therapy induced marked elevations of beta-endorphin in eight subjects; statistical analysis revealed a slight but significant increase for the whole group. This endocrine effect was not correlated with therapeutic efficacy of neuroleptic treatment.

M3 - SCORING: Zeitschriftenaufsatz

VL - 144

SP - 651

EP - 653

JO - BRIT J PSYCHIAT

JF - BRIT J PSYCHIAT

SN - 0007-1250

ER -