No correlation between neuroleptic-induced increase of beta-endorphin serum level and therapeutic efficacy in schizophrenia.
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No correlation between neuroleptic-induced increase of beta-endorphin serum level and therapeutic efficacy in schizophrenia. / Naber, Dieter; Nedopil, N; Eben, E.
in: BRIT J PSYCHIAT, Jahrgang 144, 1984, S. 651-653.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - No correlation between neuroleptic-induced increase of beta-endorphin serum level and therapeutic efficacy in schizophrenia.
AU - Naber, Dieter
AU - Nedopil, N
AU - Eben, E
PY - 1984
Y1 - 1984
N2 - In 23 acute, unmedicated, schizophrenic patients, psychotic behaviour and beta-endorphin serum level were measured before and during four weeks of neuroleptic therapy. Prior to drug treatment, beta-endorphin level of all patients was within the normal range. Neuroleptic therapy induced marked elevations of beta-endorphin in eight subjects; statistical analysis revealed a slight but significant increase for the whole group. This endocrine effect was not correlated with therapeutic efficacy of neuroleptic treatment.
AB - In 23 acute, unmedicated, schizophrenic patients, psychotic behaviour and beta-endorphin serum level were measured before and during four weeks of neuroleptic therapy. Prior to drug treatment, beta-endorphin level of all patients was within the normal range. Neuroleptic therapy induced marked elevations of beta-endorphin in eight subjects; statistical analysis revealed a slight but significant increase for the whole group. This endocrine effect was not correlated with therapeutic efficacy of neuroleptic treatment.
M3 - SCORING: Zeitschriftenaufsatz
VL - 144
SP - 651
EP - 653
JO - BRIT J PSYCHIAT
JF - BRIT J PSYCHIAT
SN - 0007-1250
ER -