No acute suppression of cerebrospinal fluid corticotropin-releasing hormone in man by cortisol administration
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No acute suppression of cerebrospinal fluid corticotropin-releasing hormone in man by cortisol administration. / Kellner, Michael; Salzwedel, Cornelie; Wortmann, Viola; Urbanowicz, Tatiana; Boelmans, Kai; Yassouridis, Alexander; Stalla, Günter K; Wiedemann, Klaus.
In: PSYCHIAT RES, Vol. 210, No. 2, 15.12.2013, p. 662-4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - No acute suppression of cerebrospinal fluid corticotropin-releasing hormone in man by cortisol administration
AU - Kellner, Michael
AU - Salzwedel, Cornelie
AU - Wortmann, Viola
AU - Urbanowicz, Tatiana
AU - Boelmans, Kai
AU - Yassouridis, Alexander
AU - Stalla, Günter K
AU - Wiedemann, Klaus
N1 - Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
PY - 2013/12/15
Y1 - 2013/12/15
N2 - Corticotropin-releasing hormone (CRH) in cerebrospinal fluid (CSF) is regarded as index of brain endocrine and behavioral functioning. We investigated the acute effects of intravenous cortisol (100mg) vs. placebo on serial CSF CRH in ten healthy men. CSF CRH concentrations were not significantly suppressed by cortisol within 3h. The origin and regulation of CSF CRH need further research.
AB - Corticotropin-releasing hormone (CRH) in cerebrospinal fluid (CSF) is regarded as index of brain endocrine and behavioral functioning. We investigated the acute effects of intravenous cortisol (100mg) vs. placebo on serial CSF CRH in ten healthy men. CSF CRH concentrations were not significantly suppressed by cortisol within 3h. The origin and regulation of CSF CRH need further research.
U2 - 10.1016/j.psychres.2013.07.003
DO - 10.1016/j.psychres.2013.07.003
M3 - SCORING: Journal article
C2 - 23896353
VL - 210
SP - 662
EP - 664
JO - PSYCHIAT RES
JF - PSYCHIAT RES
SN - 0165-1781
IS - 2
ER -