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New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus

Standard

New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus. / Steinberg, Johannes; Frings, Andreas; Mousli, Aiham; Casagrande, Maria K; Druchkiv, Vasyl; Katz, Toam; Linke, Stephan J.

In: J REFRACT SURG, Vol. 32, No. 1, 01.2016, p. 34-9.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Steinberg, J, Frings, A, Mousli, A, Casagrande, MK, Druchkiv, V, Katz, T & Linke, SJ 2016, 'New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus', J REFRACT SURG, vol. 32, no. 1, pp. 34-9. https://doi.org/10.3928/1081597X-20151207-09

APA

Steinberg, J., Frings, A., Mousli, A., Casagrande, M. K., Druchkiv, V., Katz, T., & Linke, S. J. (2016). New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus. J REFRACT SURG, 32(1), 34-9. https://doi.org/10.3928/1081597X-20151207-09

Vancouver

Steinberg J, Frings A, Mousli A, Casagrande MK, Druchkiv V, Katz T et al. New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus. J REFRACT SURG. 2016 Jan;32(1):34-9. https://doi.org/10.3928/1081597X-20151207-09

Bibtex

@article{cdc89950d3cf4d1c87a0d6752baac5b8,
title = "New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus",
abstract = "PURPOSE: To evaluate the effect of corneal cross-linking (CXL) in progressive keratoconus by applying in vivo static and dynamic Scheimpflug analyses.METHODS: In this longitudinal retrospective study, corneal topography and tomography (Pentacam HD) and dynamic Scheimpflug-based biomechanical analyses (CorvisST [CST]) of 24 eyes of 24 patients with progressive keratoconus before and 6 months after CXL were reviewed. New dynamic curve analyses, provided by Oculus Optikger{\"a}te, were performed to analyze corneal dynamics throughout the entire response to the CST air puff impulse.RESULTS: Besides subtle changes of topography and tomography, only the CorvisST predefined parameters peak distance (-0.5 mm) and radius of the intended cornea (+0.5 mm; P < .05) demonstrated statistically significant differences 6 months after CXL. Using new dynamic curve analyses, additional distinct changes of the corneal biomechanical characteristics after CXL were noted.CONCLUSIONS: Published results of corneal biomechanical changes after CXL for progressive keratoconus based on single, predefined CST parameters are inconsistent. The new dynamic curve analyses demonstrate distinct changes of the biomechanical properties of the cornea and might therefore be the next step in understanding in vivo analyses of corneal biomechanics.",
keywords = "Adolescent, Adult, Biomechanical Phenomena, Collagen, Cornea, Corneal Stroma, Corneal Topography, Cross-Linking Reagents, Elasticity, Female, Humans, Keratoconus, Longitudinal Studies, Male, Middle Aged, Photochemotherapy, Photosensitizing Agents, Refraction, Ocular, Retrospective Studies, Riboflavin, Tomography, Ultraviolet Rays, Visual Acuity, Young Adult, Journal Article",
author = "Johannes Steinberg and Andreas Frings and Aiham Mousli and Casagrande, {Maria K} and Vasyl Druchkiv and Toam Katz and Linke, {Stephan J}",
note = "Copyright 2016, SLACK Incorporated.",
year = "2016",
month = jan,
doi = "10.3928/1081597X-20151207-09",
language = "English",
volume = "32",
pages = "34--9",
journal = "J REFRACT SURG",
issn = "1081-597X",
publisher = "Slack Incorporated",
number = "1",

}

RIS

TY - JOUR

T1 - New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus

AU - Steinberg, Johannes

AU - Frings, Andreas

AU - Mousli, Aiham

AU - Casagrande, Maria K

AU - Druchkiv, Vasyl

AU - Katz, Toam

AU - Linke, Stephan J

N1 - Copyright 2016, SLACK Incorporated.

PY - 2016/1

Y1 - 2016/1

N2 - PURPOSE: To evaluate the effect of corneal cross-linking (CXL) in progressive keratoconus by applying in vivo static and dynamic Scheimpflug analyses.METHODS: In this longitudinal retrospective study, corneal topography and tomography (Pentacam HD) and dynamic Scheimpflug-based biomechanical analyses (CorvisST [CST]) of 24 eyes of 24 patients with progressive keratoconus before and 6 months after CXL were reviewed. New dynamic curve analyses, provided by Oculus Optikgeräte, were performed to analyze corneal dynamics throughout the entire response to the CST air puff impulse.RESULTS: Besides subtle changes of topography and tomography, only the CorvisST predefined parameters peak distance (-0.5 mm) and radius of the intended cornea (+0.5 mm; P < .05) demonstrated statistically significant differences 6 months after CXL. Using new dynamic curve analyses, additional distinct changes of the corneal biomechanical characteristics after CXL were noted.CONCLUSIONS: Published results of corneal biomechanical changes after CXL for progressive keratoconus based on single, predefined CST parameters are inconsistent. The new dynamic curve analyses demonstrate distinct changes of the biomechanical properties of the cornea and might therefore be the next step in understanding in vivo analyses of corneal biomechanics.

AB - PURPOSE: To evaluate the effect of corneal cross-linking (CXL) in progressive keratoconus by applying in vivo static and dynamic Scheimpflug analyses.METHODS: In this longitudinal retrospective study, corneal topography and tomography (Pentacam HD) and dynamic Scheimpflug-based biomechanical analyses (CorvisST [CST]) of 24 eyes of 24 patients with progressive keratoconus before and 6 months after CXL were reviewed. New dynamic curve analyses, provided by Oculus Optikgeräte, were performed to analyze corneal dynamics throughout the entire response to the CST air puff impulse.RESULTS: Besides subtle changes of topography and tomography, only the CorvisST predefined parameters peak distance (-0.5 mm) and radius of the intended cornea (+0.5 mm; P < .05) demonstrated statistically significant differences 6 months after CXL. Using new dynamic curve analyses, additional distinct changes of the corneal biomechanical characteristics after CXL were noted.CONCLUSIONS: Published results of corneal biomechanical changes after CXL for progressive keratoconus based on single, predefined CST parameters are inconsistent. The new dynamic curve analyses demonstrate distinct changes of the biomechanical properties of the cornea and might therefore be the next step in understanding in vivo analyses of corneal biomechanics.

KW - Adolescent

KW - Adult

KW - Biomechanical Phenomena

KW - Collagen

KW - Cornea

KW - Corneal Stroma

KW - Corneal Topography

KW - Cross-Linking Reagents

KW - Elasticity

KW - Female

KW - Humans

KW - Keratoconus

KW - Longitudinal Studies

KW - Male

KW - Middle Aged

KW - Photochemotherapy

KW - Photosensitizing Agents

KW - Refraction, Ocular

KW - Retrospective Studies

KW - Riboflavin

KW - Tomography

KW - Ultraviolet Rays

KW - Visual Acuity

KW - Young Adult

KW - Journal Article

U2 - 10.3928/1081597X-20151207-09

DO - 10.3928/1081597X-20151207-09

M3 - SCORING: Journal article

C2 - 26812712

VL - 32

SP - 34

EP - 39

JO - J REFRACT SURG

JF - J REFRACT SURG

SN - 1081-597X

IS - 1

ER -