New perspectives: systems medicine in cardiovascular disease

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New perspectives: systems medicine in cardiovascular disease. / Kramer, Frank; Just, Steffen; Zeller, Tanja.

In: BMC SYST BIOL, Vol. 12, No. 1, 25.04.2018, p. 57.

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@article{4cefa563041b4a4e9d86077195b527a7,
title = "New perspectives: systems medicine in cardiovascular disease",
abstract = "BACKGROUND: Cardiovascular diseases (CVD) represent one of the most important causes of morbidity and mortality worldwide. Innovative approaches to increase the understanding of the underpinnings of CVD promise to enhance CVD risk assessment and might pave the way to tailored therapies. Within the last years, systems medicine has emerged as a novel tool to study the genetic, molecular and physiological interactions.CONCLUSION: In this review, we provide an overview of the current molecular-experimental, epidemiological and bioinformatical tools applied in systems medicine in the cardiovascular field. We will discuss the status and challenges in implementing interdisciplinary systems medicine approaches in CVD.",
keywords = "Animals, Cardiovascular Diseases, Computational Biology, Humans, Systems Analysis",
author = "Frank Kramer and Steffen Just and Tanja Zeller",
year = "2018",
month = apr,
day = "25",
doi = "10.1186/s12918-018-0579-5",
language = "English",
volume = "12",
pages = "57",
journal = "BMC SYST BIOL",
issn = "1752-0509",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - New perspectives: systems medicine in cardiovascular disease

AU - Kramer, Frank

AU - Just, Steffen

AU - Zeller, Tanja

PY - 2018/4/25

Y1 - 2018/4/25

N2 - BACKGROUND: Cardiovascular diseases (CVD) represent one of the most important causes of morbidity and mortality worldwide. Innovative approaches to increase the understanding of the underpinnings of CVD promise to enhance CVD risk assessment and might pave the way to tailored therapies. Within the last years, systems medicine has emerged as a novel tool to study the genetic, molecular and physiological interactions.CONCLUSION: In this review, we provide an overview of the current molecular-experimental, epidemiological and bioinformatical tools applied in systems medicine in the cardiovascular field. We will discuss the status and challenges in implementing interdisciplinary systems medicine approaches in CVD.

AB - BACKGROUND: Cardiovascular diseases (CVD) represent one of the most important causes of morbidity and mortality worldwide. Innovative approaches to increase the understanding of the underpinnings of CVD promise to enhance CVD risk assessment and might pave the way to tailored therapies. Within the last years, systems medicine has emerged as a novel tool to study the genetic, molecular and physiological interactions.CONCLUSION: In this review, we provide an overview of the current molecular-experimental, epidemiological and bioinformatical tools applied in systems medicine in the cardiovascular field. We will discuss the status and challenges in implementing interdisciplinary systems medicine approaches in CVD.

KW - Animals

KW - Cardiovascular Diseases

KW - Computational Biology

KW - Humans

KW - Systems Analysis

U2 - 10.1186/s12918-018-0579-5

DO - 10.1186/s12918-018-0579-5

M3 - SCORING: Journal article

C2 - 29699591

VL - 12

SP - 57

JO - BMC SYST BIOL

JF - BMC SYST BIOL

SN - 1752-0509

IS - 1

ER -