New perspectives: systems medicine in cardiovascular disease
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New perspectives: systems medicine in cardiovascular disease. / Kramer, Frank; Just, Steffen; Zeller, Tanja.
in: BMC SYST BIOL, Jahrgang 12, Nr. 1, 25.04.2018, S. 57.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - New perspectives: systems medicine in cardiovascular disease
AU - Kramer, Frank
AU - Just, Steffen
AU - Zeller, Tanja
PY - 2018/4/25
Y1 - 2018/4/25
N2 - BACKGROUND: Cardiovascular diseases (CVD) represent one of the most important causes of morbidity and mortality worldwide. Innovative approaches to increase the understanding of the underpinnings of CVD promise to enhance CVD risk assessment and might pave the way to tailored therapies. Within the last years, systems medicine has emerged as a novel tool to study the genetic, molecular and physiological interactions.CONCLUSION: In this review, we provide an overview of the current molecular-experimental, epidemiological and bioinformatical tools applied in systems medicine in the cardiovascular field. We will discuss the status and challenges in implementing interdisciplinary systems medicine approaches in CVD.
AB - BACKGROUND: Cardiovascular diseases (CVD) represent one of the most important causes of morbidity and mortality worldwide. Innovative approaches to increase the understanding of the underpinnings of CVD promise to enhance CVD risk assessment and might pave the way to tailored therapies. Within the last years, systems medicine has emerged as a novel tool to study the genetic, molecular and physiological interactions.CONCLUSION: In this review, we provide an overview of the current molecular-experimental, epidemiological and bioinformatical tools applied in systems medicine in the cardiovascular field. We will discuss the status and challenges in implementing interdisciplinary systems medicine approaches in CVD.
KW - Animals
KW - Cardiovascular Diseases
KW - Computational Biology
KW - Humans
KW - Systems Analysis
U2 - 10.1186/s12918-018-0579-5
DO - 10.1186/s12918-018-0579-5
M3 - SCORING: Journal article
C2 - 29699591
VL - 12
SP - 57
JO - BMC SYST BIOL
JF - BMC SYST BIOL
SN - 1752-0509
IS - 1
ER -