Neuronal Activity Influences Hemodynamics in the Paraoptic Short Posterior Ciliary Arteries: A Comparison Between Healthy and Glaucoma Subjects.
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Neuronal Activity Influences Hemodynamics in the Paraoptic Short Posterior Ciliary Arteries: A Comparison Between Healthy and Glaucoma Subjects. / Zeitz, Oliver; Mayer, Jeannette; Hufnagel, Doreen; Praga, Ralf; Wagenfeld, Lars; Galambos, Peter; Wiermann, Anne; Rebel, Claudia; Richard, Gisbert; Klemm, Maren.
In: INVEST OPHTH VIS SCI, 2009.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Neuronal Activity Influences Hemodynamics in the Paraoptic Short Posterior Ciliary Arteries: A Comparison Between Healthy and Glaucoma Subjects.
AU - Zeitz, Oliver
AU - Mayer, Jeannette
AU - Hufnagel, Doreen
AU - Praga, Ralf
AU - Wagenfeld, Lars
AU - Galambos, Peter
AU - Wiermann, Anne
AU - Rebel, Claudia
AU - Richard, Gisbert
AU - Klemm, Maren
PY - 2009
Y1 - 2009
N2 - Purpose: Perfusion of the retina is adapted to the metabolic demand by neurovascular coupling. The present study investigated the presence of neurovascular coupling in the anterior part of the optic nerve in healthy and glaucoma subjects. Methods: Retrobulbar blood flow velocities were determined by color Doppler imaging (CDI). Peak-systolic and end-diastolic velocities (PSV and EDV) in the central retinal artery (CRA) or the short posterior ciliary artery (SPCA) were the primary readout. CDI measurements were performed shortly before, during, immediately after, 60 s after, and 120 s after a 10-Hz flicker stimulation of the retina. Results: Thirty-five glaucoma patients and 44 healthy control subjects were included in the study. In the SPCA of healthy controls, flicker stimulation led to a rise of PSV from 9.7+/-0.8 to 12.5+/-0.8 cm/s (P
AB - Purpose: Perfusion of the retina is adapted to the metabolic demand by neurovascular coupling. The present study investigated the presence of neurovascular coupling in the anterior part of the optic nerve in healthy and glaucoma subjects. Methods: Retrobulbar blood flow velocities were determined by color Doppler imaging (CDI). Peak-systolic and end-diastolic velocities (PSV and EDV) in the central retinal artery (CRA) or the short posterior ciliary artery (SPCA) were the primary readout. CDI measurements were performed shortly before, during, immediately after, 60 s after, and 120 s after a 10-Hz flicker stimulation of the retina. Results: Thirty-five glaucoma patients and 44 healthy control subjects were included in the study. In the SPCA of healthy controls, flicker stimulation led to a rise of PSV from 9.7+/-0.8 to 12.5+/-0.8 cm/s (P
U2 - 10.1167/iovs.09-3696
DO - 10.1167/iovs.09-3696
M3 - SCORING: Zeitschriftenaufsatz
JO - INVEST OPHTH VIS SCI
JF - INVEST OPHTH VIS SCI
SN - 0146-0404
ER -