Neuronal Activity Influences Hemodynamics in the Paraoptic Short Posterior Ciliary Arteries: A Comparison Between Healthy and Glaucoma Subjects.

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Neuronal Activity Influences Hemodynamics in the Paraoptic Short Posterior Ciliary Arteries: A Comparison Between Healthy and Glaucoma Subjects. / Zeitz, Oliver; Mayer, Jeannette; Hufnagel, Doreen; Praga, Ralf; Wagenfeld, Lars; Galambos, Peter; Wiermann, Anne; Rebel, Claudia; Richard, Gisbert; Klemm, Maren.

in: INVEST OPHTH VIS SCI, 2009.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{fe484264b0024f0e91970687ebb47e24,
title = "Neuronal Activity Influences Hemodynamics in the Paraoptic Short Posterior Ciliary Arteries: A Comparison Between Healthy and Glaucoma Subjects.",
abstract = "Purpose: Perfusion of the retina is adapted to the metabolic demand by neurovascular coupling. The present study investigated the presence of neurovascular coupling in the anterior part of the optic nerve in healthy and glaucoma subjects. Methods: Retrobulbar blood flow velocities were determined by color Doppler imaging (CDI). Peak-systolic and end-diastolic velocities (PSV and EDV) in the central retinal artery (CRA) or the short posterior ciliary artery (SPCA) were the primary readout. CDI measurements were performed shortly before, during, immediately after, 60 s after, and 120 s after a 10-Hz flicker stimulation of the retina. Results: Thirty-five glaucoma patients and 44 healthy control subjects were included in the study. In the SPCA of healthy controls, flicker stimulation led to a rise of PSV from 9.7+/-0.8 to 12.5+/-0.8 cm/s (P",
author = "Oliver Zeitz and Jeannette Mayer and Doreen Hufnagel and Ralf Praga and Lars Wagenfeld and Peter Galambos and Anne Wiermann and Claudia Rebel and Gisbert Richard and Maren Klemm",
year = "2009",
doi = "10.1167/iovs.09-3696",
language = "Deutsch",
journal = "INVEST OPHTH VIS SCI",
issn = "0146-0404",
publisher = "Association for Research in Vision and Ophthalmology Inc.",

}

RIS

TY - JOUR

T1 - Neuronal Activity Influences Hemodynamics in the Paraoptic Short Posterior Ciliary Arteries: A Comparison Between Healthy and Glaucoma Subjects.

AU - Zeitz, Oliver

AU - Mayer, Jeannette

AU - Hufnagel, Doreen

AU - Praga, Ralf

AU - Wagenfeld, Lars

AU - Galambos, Peter

AU - Wiermann, Anne

AU - Rebel, Claudia

AU - Richard, Gisbert

AU - Klemm, Maren

PY - 2009

Y1 - 2009

N2 - Purpose: Perfusion of the retina is adapted to the metabolic demand by neurovascular coupling. The present study investigated the presence of neurovascular coupling in the anterior part of the optic nerve in healthy and glaucoma subjects. Methods: Retrobulbar blood flow velocities were determined by color Doppler imaging (CDI). Peak-systolic and end-diastolic velocities (PSV and EDV) in the central retinal artery (CRA) or the short posterior ciliary artery (SPCA) were the primary readout. CDI measurements were performed shortly before, during, immediately after, 60 s after, and 120 s after a 10-Hz flicker stimulation of the retina. Results: Thirty-five glaucoma patients and 44 healthy control subjects were included in the study. In the SPCA of healthy controls, flicker stimulation led to a rise of PSV from 9.7+/-0.8 to 12.5+/-0.8 cm/s (P

AB - Purpose: Perfusion of the retina is adapted to the metabolic demand by neurovascular coupling. The present study investigated the presence of neurovascular coupling in the anterior part of the optic nerve in healthy and glaucoma subjects. Methods: Retrobulbar blood flow velocities were determined by color Doppler imaging (CDI). Peak-systolic and end-diastolic velocities (PSV and EDV) in the central retinal artery (CRA) or the short posterior ciliary artery (SPCA) were the primary readout. CDI measurements were performed shortly before, during, immediately after, 60 s after, and 120 s after a 10-Hz flicker stimulation of the retina. Results: Thirty-five glaucoma patients and 44 healthy control subjects were included in the study. In the SPCA of healthy controls, flicker stimulation led to a rise of PSV from 9.7+/-0.8 to 12.5+/-0.8 cm/s (P

U2 - 10.1167/iovs.09-3696

DO - 10.1167/iovs.09-3696

M3 - SCORING: Zeitschriftenaufsatz

JO - INVEST OPHTH VIS SCI

JF - INVEST OPHTH VIS SCI

SN - 0146-0404

ER -