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Neuroleptic withdrawal in chronic schizophrenia: CT and endocrine variables relating to psychopathology.

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Neuroleptic withdrawal in chronic schizophrenia: CT and endocrine variables relating to psychopathology. / Naber, Dieter; Albus, M; Bürke, H; Müller-Spahn, F; Münch, U; Reinertshofer, T; Wissmann, J; Ackenheil, M.

In: PSYCHIAT RES, Vol. 16, No. 3, 3, 1985, p. 207-219.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Naber, D, Albus, M, Bürke, H, Müller-Spahn, F, Münch, U, Reinertshofer, T, Wissmann, J & Ackenheil, M 1985, 'Neuroleptic withdrawal in chronic schizophrenia: CT and endocrine variables relating to psychopathology.', PSYCHIAT RES, vol. 16, no. 3, 3, pp. 207-219. <http://www.ncbi.nlm.nih.gov/pubmed/2868473?dopt=Citation>

APA

Naber, D., Albus, M., Bürke, H., Müller-Spahn, F., Münch, U., Reinertshofer, T., Wissmann, J., & Ackenheil, M. (1985). Neuroleptic withdrawal in chronic schizophrenia: CT and endocrine variables relating to psychopathology. PSYCHIAT RES, 16(3), 207-219. [3]. http://www.ncbi.nlm.nih.gov/pubmed/2868473?dopt=Citation

Vancouver

Naber D, Albus M, Bürke H, Müller-Spahn F, Münch U, Reinertshofer T et al. Neuroleptic withdrawal in chronic schizophrenia: CT and endocrine variables relating to psychopathology. PSYCHIAT RES. 1985;16(3):207-219. 3.

Bibtex

@article{06673fdf534e474c8437f0c7a4556ec5,
title = "Neuroleptic withdrawal in chronic schizophrenia: CT and endocrine variables relating to psychopathology.",
abstract = "The psychopathology of 36 chronic, schizophrenic patients who had been on maintenance neuroleptics was rated during neuroleptic therapy and after 12 days of neuroleptic withdrawal. At both times, hormonal serum levels were also determined. Moreover, in 27 of these patients, ventricle-brain ratio, maximal width of the third ventricle, and sulcal widening were measured on computed tomography (CT). Neuroleptic withdrawal resulted in individually different psychopathological changes: 7 patients improved, 11 worsened. Within the whole group, thought disorder deteriorated, and anergia improved. Levels of cortisol and beta-endorphin increased; those of prolactin and norepinephrine decreased. The majority of patients showed ventricular enlargement, which was marginally related to reduced thought disorder. CT and endocrine variables were slightly related to psychopathology or psychopathological effects of neuroleptic withdrawal.",
author = "Dieter Naber and M Albus and H B{\"u}rke and F M{\"u}ller-Spahn and U M{\"u}nch and T Reinertshofer and J Wissmann and M Ackenheil",
year = "1985",
language = "Deutsch",
volume = "16",
pages = "207--219",
journal = "PSYCHIAT RES",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Neuroleptic withdrawal in chronic schizophrenia: CT and endocrine variables relating to psychopathology.

AU - Naber, Dieter

AU - Albus, M

AU - Bürke, H

AU - Müller-Spahn, F

AU - Münch, U

AU - Reinertshofer, T

AU - Wissmann, J

AU - Ackenheil, M

PY - 1985

Y1 - 1985

N2 - The psychopathology of 36 chronic, schizophrenic patients who had been on maintenance neuroleptics was rated during neuroleptic therapy and after 12 days of neuroleptic withdrawal. At both times, hormonal serum levels were also determined. Moreover, in 27 of these patients, ventricle-brain ratio, maximal width of the third ventricle, and sulcal widening were measured on computed tomography (CT). Neuroleptic withdrawal resulted in individually different psychopathological changes: 7 patients improved, 11 worsened. Within the whole group, thought disorder deteriorated, and anergia improved. Levels of cortisol and beta-endorphin increased; those of prolactin and norepinephrine decreased. The majority of patients showed ventricular enlargement, which was marginally related to reduced thought disorder. CT and endocrine variables were slightly related to psychopathology or psychopathological effects of neuroleptic withdrawal.

AB - The psychopathology of 36 chronic, schizophrenic patients who had been on maintenance neuroleptics was rated during neuroleptic therapy and after 12 days of neuroleptic withdrawal. At both times, hormonal serum levels were also determined. Moreover, in 27 of these patients, ventricle-brain ratio, maximal width of the third ventricle, and sulcal widening were measured on computed tomography (CT). Neuroleptic withdrawal resulted in individually different psychopathological changes: 7 patients improved, 11 worsened. Within the whole group, thought disorder deteriorated, and anergia improved. Levels of cortisol and beta-endorphin increased; those of prolactin and norepinephrine decreased. The majority of patients showed ventricular enlargement, which was marginally related to reduced thought disorder. CT and endocrine variables were slightly related to psychopathology or psychopathological effects of neuroleptic withdrawal.

M3 - SCORING: Zeitschriftenaufsatz

VL - 16

SP - 207

EP - 219

JO - PSYCHIAT RES

JF - PSYCHIAT RES

SN - 0165-1781

IS - 3

M1 - 3

ER -