Neural correlates of impaired volitional action control in schizophrenia patients

Julia Bender; Benedikt Reuter; David Möllers; Christian Kaufmann; Jürgen Gallinat; Norbert Kathmann

doi:10.1111/psyp.12060

Neural correlates of impaired volitional action control in schizophrenia patients

Standard

Neural correlates of impaired volitional action control in schizophrenia patients. / Bender, Julia; Reuter, Benedikt; Möllers, David; Kaufmann, Christian; Gallinat, Jürgen; Kathmann, Norbert.

In: PSYCHOPHYSIOLOGY, Vol. 50, No. 9, 01.09.2013, p. 872-84.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Bender, J, Reuter, B, Möllers, D, Kaufmann, C, Gallinat, J & Kathmann, N 2013, 'Neural correlates of impaired volitional action control in schizophrenia patients', PSYCHOPHYSIOLOGY, vol. 50, no. 9, pp. 872-84. https://doi.org/10.1111/psyp.12060

APA

Bender, J., Reuter, B., Möllers, D., Kaufmann, C., Gallinat, J., & Kathmann, N. (2013). Neural correlates of impaired volitional action control in schizophrenia patients. PSYCHOPHYSIOLOGY, 50(9), 872-84. https://doi.org/10.1111/psyp.12060

Vancouver

Bender J, Reuter B, Möllers D, Kaufmann C, Gallinat J, Kathmann N. Neural correlates of impaired volitional action control in schizophrenia patients. PSYCHOPHYSIOLOGY. 2013 Sep 1;50(9):872-84. https://doi.org/10.1111/psyp.12060

Bibtex

@article{f53c445fe35a4c72aee27afbb4ed7827,

title = "Neural correlates of impaired volitional action control in schizophrenia patients",

abstract = "Slowed initiation of volitional but not visually guided saccades indicates impaired volitional action control in schizophrenia patients (SZ). The present study aimed at identifying neural correlates of this specific deficit. Fourteen SZ and 13 healthy control participants (HC) underwent functional magnetic resonance imaging while performing volitional and visually guided saccades. SZ showed increased latencies in volitional but not in visually guided saccades. Brain activation during volitional saccades compared to visually guided saccades was increased in SZ compared to HC in several areas: the supplementary eye fields, suggesting inefficient production of volitional saccades; the prefrontal cortex, pointing to altered top down control on complex eye movements; and the left middle temporal area, suggesting changes in early sensory and attention processing during the volitional control of saccades in SZ.",

keywords = "Adult, Cerebrum, Cues, Executive Function, Female, Functional Neuroimaging, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Saccades, Schizophrenia, Time Factors, Volition",

author = "Julia Bender and Benedikt Reuter and David M{\"o}llers and Christian Kaufmann and J{\"u}rgen Gallinat and Norbert Kathmann",

note = "Copyright {\textcopyright} 2013 Society for Psychophysiological Research.",

year = "2013",

month = sep,

day = "1",

doi = "10.1111/psyp.12060",

language = "English",

volume = "50",

pages = "872--84",

journal = "PSYCHOPHYSIOLOGY",

issn = "0048-5772",

publisher = "Wiley-Blackwell",

number = "9",

}

RIS

TY - JOUR

T1 - Neural correlates of impaired volitional action control in schizophrenia patients

AU - Bender, Julia

AU - Reuter, Benedikt

AU - Möllers, David

AU - Kaufmann, Christian

AU - Gallinat, Jürgen

AU - Kathmann, Norbert

PY - 2013/9/1

Y1 - 2013/9/1

N2 - Slowed initiation of volitional but not visually guided saccades indicates impaired volitional action control in schizophrenia patients (SZ). The present study aimed at identifying neural correlates of this specific deficit. Fourteen SZ and 13 healthy control participants (HC) underwent functional magnetic resonance imaging while performing volitional and visually guided saccades. SZ showed increased latencies in volitional but not in visually guided saccades. Brain activation during volitional saccades compared to visually guided saccades was increased in SZ compared to HC in several areas: the supplementary eye fields, suggesting inefficient production of volitional saccades; the prefrontal cortex, pointing to altered top down control on complex eye movements; and the left middle temporal area, suggesting changes in early sensory and attention processing during the volitional control of saccades in SZ.

AB - Slowed initiation of volitional but not visually guided saccades indicates impaired volitional action control in schizophrenia patients (SZ). The present study aimed at identifying neural correlates of this specific deficit. Fourteen SZ and 13 healthy control participants (HC) underwent functional magnetic resonance imaging while performing volitional and visually guided saccades. SZ showed increased latencies in volitional but not in visually guided saccades. Brain activation during volitional saccades compared to visually guided saccades was increased in SZ compared to HC in several areas: the supplementary eye fields, suggesting inefficient production of volitional saccades; the prefrontal cortex, pointing to altered top down control on complex eye movements; and the left middle temporal area, suggesting changes in early sensory and attention processing during the volitional control of saccades in SZ.

KW - Adult

KW - Cerebrum

KW - Cues

KW - Executive Function

KW - Female

KW - Functional Neuroimaging

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Middle Aged

KW - Saccades

KW - Schizophrenia

KW - Time Factors

KW - Volition

U2 - 10.1111/psyp.12060

DO - 10.1111/psyp.12060

M3 - SCORING: Journal article

C2 - 23790023

VL - 50

SP - 872

EP - 884

JO - PSYCHOPHYSIOLOGY

JF - PSYCHOPHYSIOLOGY

SN - 0048-5772

IS - 9

ER -