Nephrogenic systemic fibrosis
Related Research units
Abstract
Nephrogenic systemic fibrosis (NSF) is an iatrogenic fibrosing disorder that primarily affects individuals with chronic kidney disease (CKD) following exposure to gadolinium-based contrast agents (GBCAs) during imaging procedures. NSF is characterised by skin thickening, tethering and hyperpigmentation; flexion contractures of joints; and extracutaneous fibrosis. This article reviews the history, clinical manifestations, epidemiology, histopathology and pathophysiology of this disabling disease.
Bibliographical data
Original language | English |
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ISSN | 1521-6942 |
DOIs | |
Publication status | Published - 08.2012 |
Comment Deanary
Copyright © 2012 Elsevier Ltd. All rights reserved.
PubMed | 23040363 |
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