Necrobiosis and T-lymphocyte infiltration in retrieved aseptically loosened metal-on-polyethylene arthroplasties.
Standard
Necrobiosis and T-lymphocyte infiltration in retrieved aseptically loosened metal-on-polyethylene arthroplasties. / von Domarus, Christoph; Rosenberg, Jens P; Rüther, Wolfgang; Zustin, Jozef.
In: ACTA ORTHOP, Vol. 82, No. 5, 5, 2011, p. 596-601.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Necrobiosis and T-lymphocyte infiltration in retrieved aseptically loosened metal-on-polyethylene arthroplasties.
AU - von Domarus, Christoph
AU - Rosenberg, Jens P
AU - Rüther, Wolfgang
AU - Zustin, Jozef
PY - 2011
Y1 - 2011
N2 - Soft tissue necrobiosis and T-lymphocyte infiltration within the periprosthetic soft tissue have been linked to a suggested hypersensitivity reaction of the delayed-type following the metal-on-metal arthroplasty. While we observed both synovial necrobiosis and lymphocyte infiltrates in synovial tissues with failed metal-on-polyethylene prostheses, we hypothesized that both findings are unspecific for metal-on-metal bearing coupes. Thus, we wished to quantify the extent of necrobiosis and the amount of T-lymphocyte infiltration in aseptically loosened metal-on-polyethylene prostheses.
AB - Soft tissue necrobiosis and T-lymphocyte infiltration within the periprosthetic soft tissue have been linked to a suggested hypersensitivity reaction of the delayed-type following the metal-on-metal arthroplasty. While we observed both synovial necrobiosis and lymphocyte infiltrates in synovial tissues with failed metal-on-polyethylene prostheses, we hypothesized that both findings are unspecific for metal-on-metal bearing coupes. Thus, we wished to quantify the extent of necrobiosis and the amount of T-lymphocyte infiltration in aseptically loosened metal-on-polyethylene prostheses.
KW - Humans
KW - Aged
KW - Middle Aged
KW - Reoperation
KW - Prosthesis Design
KW - Prosthesis Failure
KW - Arthroplasty, Replacement, Hip/adverse effects/methods
KW - Arthroplasty, Replacement, Knee/adverse effects/methods
KW - Biocompatible Materials/adverse effects
KW - Hip Prosthesis/adverse effects
KW - Hypersensitivity/etiology
KW - Knee Prosthesis/adverse effects
KW - Lymphocyte Count
KW - Metals/adverse effects
KW - Necrobiotic Disorders/chemically induced/immunology/pathology
KW - Polyethylenes/adverse effects
KW - Synovial Membrane/pathology
KW - T-Lymphocytes/immunology/pathology
KW - Humans
KW - Aged
KW - Middle Aged
KW - Reoperation
KW - Prosthesis Design
KW - Prosthesis Failure
KW - Arthroplasty, Replacement, Hip/adverse effects/methods
KW - Arthroplasty, Replacement, Knee/adverse effects/methods
KW - Biocompatible Materials/adverse effects
KW - Hip Prosthesis/adverse effects
KW - Hypersensitivity/etiology
KW - Knee Prosthesis/adverse effects
KW - Lymphocyte Count
KW - Metals/adverse effects
KW - Necrobiotic Disorders/chemically induced/immunology/pathology
KW - Polyethylenes/adverse effects
KW - Synovial Membrane/pathology
KW - T-Lymphocytes/immunology/pathology
U2 - 10.3109/17453674.2011.625534
DO - 10.3109/17453674.2011.625534
M3 - SCORING: Journal article
VL - 82
SP - 596
EP - 601
JO - ACTA ORTHOP
JF - ACTA ORTHOP
SN - 1745-3674
IS - 5
M1 - 5
ER -