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Nachweis und biologische Bedeutung von Viren und Onkogenen bei Uteruskarzinomen

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Nachweis und biologische Bedeutung von Viren und Onkogenen bei Uteruskarzinomen. / Milde-Langosch, K; Wilckens, C; Brack, T; Löning, T.

In: Verh Dtsch Ges Pathol, Vol. 75, 1991, p. 363-365.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Milde-Langosch, K, Wilckens, C, Brack, T & Löning, T 1991, 'Nachweis und biologische Bedeutung von Viren und Onkogenen bei Uteruskarzinomen', Verh Dtsch Ges Pathol, vol. 75, pp. 363-365. <http://www.ncbi.nlm.nih.gov/pubmed/1724842?dopt=Citation>

APA

Milde-Langosch, K., Wilckens, C., Brack, T., & Löning, T. (1991). Nachweis und biologische Bedeutung von Viren und Onkogenen bei Uteruskarzinomen. Verh Dtsch Ges Pathol, 75, 363-365. http://www.ncbi.nlm.nih.gov/pubmed/1724842?dopt=Citation

Vancouver

Milde-Langosch K, Wilckens C, Brack T, Löning T. Nachweis und biologische Bedeutung von Viren und Onkogenen bei Uteruskarzinomen. Verh Dtsch Ges Pathol. 1991;75:363-365.

Bibtex

@article{69f54d996fca42d49f04a30bfd9ee7d9,
title = "Nachweis und biologische Bedeutung von Viren und Onkogenen bei Uteruskarzinomen",
abstract = "Premalignant and malignant lesions of the cervix uteri and endometrium were analyzed for the presence of human papillomavirus (HPV) DNA and c-myc or c-erbB2/neu oncogene expression. HPV DNA was detected by PCR in 100% of the cervical carcinomas and CIN lesions, but also in endometrial lesions (3/8 adenocarcinomas, two hyperplasias and one adenomyosis uteri). Myc-overexpression was found in 25-30% of the cervical carcinomas and severe dysplasias, but not in endometrial lesions. C-erbB2 was overexpressed in 4/11 endometrial carcinomas and 3/19 CIN3 lesions. The implications of these results are discussed.",
keywords = "DNA, Viral, Endometrial Neoplasms, Female, Genes, myc, Humans, Oncogenes, Papillomaviridae, Precancerous Conditions, Proto-Oncogene Proteins, Proto-Oncogenes, Receptor, ErbB-2, Tumor Markers, Biological, Uterine Cervical Neoplasms, Uterine Neoplasms",
author = "K Milde-Langosch and C Wilckens and T Brack and T L{\"o}ning",
year = "1991",
language = "Deutsch",
volume = "75",
pages = "363--365",

}

RIS

TY - JOUR

T1 - Nachweis und biologische Bedeutung von Viren und Onkogenen bei Uteruskarzinomen

AU - Milde-Langosch, K

AU - Wilckens, C

AU - Brack, T

AU - Löning, T

PY - 1991

Y1 - 1991

N2 - Premalignant and malignant lesions of the cervix uteri and endometrium were analyzed for the presence of human papillomavirus (HPV) DNA and c-myc or c-erbB2/neu oncogene expression. HPV DNA was detected by PCR in 100% of the cervical carcinomas and CIN lesions, but also in endometrial lesions (3/8 adenocarcinomas, two hyperplasias and one adenomyosis uteri). Myc-overexpression was found in 25-30% of the cervical carcinomas and severe dysplasias, but not in endometrial lesions. C-erbB2 was overexpressed in 4/11 endometrial carcinomas and 3/19 CIN3 lesions. The implications of these results are discussed.

AB - Premalignant and malignant lesions of the cervix uteri and endometrium were analyzed for the presence of human papillomavirus (HPV) DNA and c-myc or c-erbB2/neu oncogene expression. HPV DNA was detected by PCR in 100% of the cervical carcinomas and CIN lesions, but also in endometrial lesions (3/8 adenocarcinomas, two hyperplasias and one adenomyosis uteri). Myc-overexpression was found in 25-30% of the cervical carcinomas and severe dysplasias, but not in endometrial lesions. C-erbB2 was overexpressed in 4/11 endometrial carcinomas and 3/19 CIN3 lesions. The implications of these results are discussed.

KW - DNA, Viral

KW - Endometrial Neoplasms

KW - Female

KW - Genes, myc

KW - Humans

KW - Oncogenes

KW - Papillomaviridae

KW - Precancerous Conditions

KW - Proto-Oncogene Proteins

KW - Proto-Oncogenes

KW - Receptor, ErbB-2

KW - Tumor Markers, Biological

KW - Uterine Cervical Neoplasms

KW - Uterine Neoplasms

M3 - SCORING: Zeitschriftenaufsatz

C2 - 1724842

VL - 75

SP - 363

EP - 365

ER -