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Myocardial tissue Engineering: in vitro models

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Myocardial tissue Engineering: in vitro models. / Vunjak Novakovic, Gordana; Eschenhagen, Thomas; Mummery, Christine.

In: CSH PERSPECT MED, Vol. 4, No. 3, 01.03.2014.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Vunjak Novakovic, G, Eschenhagen, T & Mummery, C 2014, 'Myocardial tissue Engineering: in vitro models', CSH PERSPECT MED, vol. 4, no. 3. https://doi.org/10.1101/cshperspect.a014076

APA

Vunjak Novakovic, G., Eschenhagen, T., & Mummery, C. (2014). Myocardial tissue Engineering: in vitro models. CSH PERSPECT MED, 4(3). https://doi.org/10.1101/cshperspect.a014076

Vancouver

Vunjak Novakovic G, Eschenhagen T, Mummery C. Myocardial tissue Engineering: in vitro models. CSH PERSPECT MED. 2014 Mar 1;4(3). https://doi.org/10.1101/cshperspect.a014076

Bibtex

@article{dce986c1b5dd4530822745896c273455,
title = "Myocardial tissue Engineering: in vitro models",
abstract = "Modeling integrated human physiology in vitro is a formidable task not yet achieved with any of the existing cell/tissue systems. However, tissue engineering is becoming increasingly successful at authentic representation of the actual environmental milieu of tissue development, regeneration and disease progression, and in providing real-time insights into morphogenic events. Functional human tissue units engineered to combine biological fidelity with the high-throughput screening and real-time measurement of physiological responses are poised to transform drug screening and predictive modeling of disease. In this review, we focus on the in vitro engineering of functional human myocardium that mimics heart tissue for analysis of myocardial function, in the context of physiological studies, drug screening for therapeutics, and safety pharmacology.",
author = "{Vunjak Novakovic}, Gordana and Thomas Eschenhagen and Christine Mummery",
year = "2014",
month = mar,
day = "1",
doi = "10.1101/cshperspect.a014076",
language = "English",
volume = "4",
journal = "CSH PERSPECT MED",
issn = "2157-1422",
publisher = "Cold Spring Harbor Laboratory Press",
number = "3",

}

RIS

TY - JOUR

T1 - Myocardial tissue Engineering: in vitro models

AU - Vunjak Novakovic, Gordana

AU - Eschenhagen, Thomas

AU - Mummery, Christine

PY - 2014/3/1

Y1 - 2014/3/1

N2 - Modeling integrated human physiology in vitro is a formidable task not yet achieved with any of the existing cell/tissue systems. However, tissue engineering is becoming increasingly successful at authentic representation of the actual environmental milieu of tissue development, regeneration and disease progression, and in providing real-time insights into morphogenic events. Functional human tissue units engineered to combine biological fidelity with the high-throughput screening and real-time measurement of physiological responses are poised to transform drug screening and predictive modeling of disease. In this review, we focus on the in vitro engineering of functional human myocardium that mimics heart tissue for analysis of myocardial function, in the context of physiological studies, drug screening for therapeutics, and safety pharmacology.

AB - Modeling integrated human physiology in vitro is a formidable task not yet achieved with any of the existing cell/tissue systems. However, tissue engineering is becoming increasingly successful at authentic representation of the actual environmental milieu of tissue development, regeneration and disease progression, and in providing real-time insights into morphogenic events. Functional human tissue units engineered to combine biological fidelity with the high-throughput screening and real-time measurement of physiological responses are poised to transform drug screening and predictive modeling of disease. In this review, we focus on the in vitro engineering of functional human myocardium that mimics heart tissue for analysis of myocardial function, in the context of physiological studies, drug screening for therapeutics, and safety pharmacology.

U2 - 10.1101/cshperspect.a014076

DO - 10.1101/cshperspect.a014076

M3 - SCORING: Journal article

C2 - 24591534

VL - 4

JO - CSH PERSPECT MED

JF - CSH PERSPECT MED

SN - 2157-1422

IS - 3

ER -