Myocardial tissue engineering for cardiac repair

Simon Pecha; Thomas Eschenhagen; Hermann Reichenspurner

doi:10.1016/j.healun.2015.12.007

Myocardial tissue engineering for cardiac repair

Standard

Myocardial tissue engineering for cardiac repair. / Pecha, Simon ; Eschenhagen, Thomas ; Reichenspurner, Hermann.

In: J HEART LUNG TRANSPL, Vol. 35, No. 3, 03.2016, p. 294-298.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Pecha, S , Eschenhagen, T & Reichenspurner, H 2016, 'Myocardial tissue engineering for cardiac repair', J HEART LUNG TRANSPL, vol. 35, no. 3, pp. 294-298. https://doi.org/10.1016/j.healun.2015.12.007

APA

Pecha, S., Eschenhagen, T., & Reichenspurner, H. (2016). Myocardial tissue engineering for cardiac repair. J HEART LUNG TRANSPL, 35(3), 294-298. https://doi.org/10.1016/j.healun.2015.12.007

Vancouver

Pecha S , Eschenhagen T , Reichenspurner H. Myocardial tissue engineering for cardiac repair. J HEART LUNG TRANSPL. 2016 Mar;35(3):294-298. https://doi.org/10.1016/j.healun.2015.12.007

Bibtex

@article{b014f24b01b441bb88f14071b2aca381,

title = "Myocardial tissue engineering for cardiac repair",

abstract = "The number of patients with heart failure is increasing in the aging population. Heart transplantation remains the only curative treatment option for patients with end-stage heart failure. Because of an organ donor shortage, new organ-independent treatment options are necessary. Different approaches to cardiac repair therapies have been developed and optimized in recent years. One of these promising approaches is myocardial tissue engineering, which refers to the creation of 3-dimensional engineered heart tissue in vitro. This perspective provides an overview of different approaches to tissue engineering, including essentials to improve tissue quality and choice of ideal cell source, as well as an overview of in vitro and in vivo studies. Several hurdles that have to be overcome before clinical application of engineered heart tissue might become a realistic scenario are also addressed.",

keywords = "Editorial",

author = "Simon Pecha and Thomas Eschenhagen and Hermann Reichenspurner",

year = "2016",

month = mar,

doi = "10.1016/j.healun.2015.12.007",

language = "English",

volume = "35",

pages = "294--298",

journal = "J HEART LUNG TRANSPL",

issn = "1053-2498",

publisher = "Elsevier USA",

number = "3",

}

RIS

TY - JOUR

T1 - Myocardial tissue engineering for cardiac repair

AU - Pecha, Simon

AU - Eschenhagen, Thomas

AU - Reichenspurner, Hermann

PY - 2016/3

Y1 - 2016/3

N2 - The number of patients with heart failure is increasing in the aging population. Heart transplantation remains the only curative treatment option for patients with end-stage heart failure. Because of an organ donor shortage, new organ-independent treatment options are necessary. Different approaches to cardiac repair therapies have been developed and optimized in recent years. One of these promising approaches is myocardial tissue engineering, which refers to the creation of 3-dimensional engineered heart tissue in vitro. This perspective provides an overview of different approaches to tissue engineering, including essentials to improve tissue quality and choice of ideal cell source, as well as an overview of in vitro and in vivo studies. Several hurdles that have to be overcome before clinical application of engineered heart tissue might become a realistic scenario are also addressed.

AB - The number of patients with heart failure is increasing in the aging population. Heart transplantation remains the only curative treatment option for patients with end-stage heart failure. Because of an organ donor shortage, new organ-independent treatment options are necessary. Different approaches to cardiac repair therapies have been developed and optimized in recent years. One of these promising approaches is myocardial tissue engineering, which refers to the creation of 3-dimensional engineered heart tissue in vitro. This perspective provides an overview of different approaches to tissue engineering, including essentials to improve tissue quality and choice of ideal cell source, as well as an overview of in vitro and in vivo studies. Several hurdles that have to be overcome before clinical application of engineered heart tissue might become a realistic scenario are also addressed.

KW - Editorial

U2 - 10.1016/j.healun.2015.12.007

DO - 10.1016/j.healun.2015.12.007

M3 - SCORING: Journal article

C2 - 26856673

VL - 35

SP - 294

EP - 298

JO - J HEART LUNG TRANSPL

JF - J HEART LUNG TRANSPL

SN - 1053-2498

IS - 3

ER -