Mucoepidermoid carcinoma of salivary gland origin
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Mucoepidermoid carcinoma of salivary gland origin : classification, clinical-pathological correlation, treatment results and long-term follow-up in 55 patients. / Plambeck, K; Friedrich, R E; Schmelzle, R.
In: J CRANIO MAXILL SURG, Vol. 24, No. 3, 01.06.1996, p. 133-9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Mucoepidermoid carcinoma of salivary gland origin
T2 - classification, clinical-pathological correlation, treatment results and long-term follow-up in 55 patients
AU - Plambeck, K
AU - Friedrich, R E
AU - Schmelzle, R
PY - 1996/6/1
Y1 - 1996/6/1
N2 - Over a period of 30 years, 55 patients with mucoepidermoid carcinomas (MEC) of the salivary glands underwent surgical treatment. Reclassified TNM-stage (Hermanek et al., 1992) at the time of initial diagnosis varied (T0: 0, T1: 26, T2: 20, T3: 2, T4: 7; N0: 49, N1: 4, N2: 2; M0: 53, M1: 2). In 46% (n = 24), the history of symptoms ranged from 6 months to 2 years without any specificity of features. The therapy of choice is a radical ablative surgery of the primary tumour. The resection of the related lymphatic system has to be included in the therapeutic concept in patients suspected of having metastases of the regional lymph nodes. The prognosis is excellent in patients with a localized manifestation of the disease only. Our patients who died for reasons of tumour metastasis had all been classified as stage III or IV at the time initial diagnosis (n = 5). Distant metastases are rarely found even decades after surgical therapy (n = 1). This is why a long-term follow-up is recommended for patients with MEC of the salivary glands.
AB - Over a period of 30 years, 55 patients with mucoepidermoid carcinomas (MEC) of the salivary glands underwent surgical treatment. Reclassified TNM-stage (Hermanek et al., 1992) at the time of initial diagnosis varied (T0: 0, T1: 26, T2: 20, T3: 2, T4: 7; N0: 49, N1: 4, N2: 2; M0: 53, M1: 2). In 46% (n = 24), the history of symptoms ranged from 6 months to 2 years without any specificity of features. The therapy of choice is a radical ablative surgery of the primary tumour. The resection of the related lymphatic system has to be included in the therapeutic concept in patients suspected of having metastases of the regional lymph nodes. The prognosis is excellent in patients with a localized manifestation of the disease only. Our patients who died for reasons of tumour metastasis had all been classified as stage III or IV at the time initial diagnosis (n = 5). Distant metastases are rarely found even decades after surgical therapy (n = 1). This is why a long-term follow-up is recommended for patients with MEC of the salivary glands.
KW - Adolescent
KW - Adult
KW - Aged
KW - Carcinoma, Mucoepidermoid
KW - Child
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Longitudinal Studies
KW - Lymph Node Excision
KW - Male
KW - Middle Aged
KW - Neoplasm Recurrence, Local
KW - Neoplasm Staging
KW - Parotid Gland
KW - Parotid Neoplasms
KW - Prognosis
KW - Salivary Gland Neoplasms
KW - Salivary Glands
KW - Survival Rate
KW - Treatment Outcome
M3 - SCORING: Journal article
C2 - 8842902
VL - 24
SP - 133
EP - 139
JO - J CRANIO MAXILL SURG
JF - J CRANIO MAXILL SURG
SN - 1010-5182
IS - 3
ER -