Mucoepidermoid carcinoma of salivary gland origin

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Mucoepidermoid carcinoma of salivary gland origin : classification, clinical-pathological correlation, treatment results and long-term follow-up in 55 patients. / Plambeck, K; Friedrich, R E; Schmelzle, R.

in: J CRANIO MAXILL SURG, Jahrgang 24, Nr. 3, 01.06.1996, S. 133-9.

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@article{48f561dfb801489081ff22e12d5c2b92,
title = "Mucoepidermoid carcinoma of salivary gland origin: classification, clinical-pathological correlation, treatment results and long-term follow-up in 55 patients",
abstract = "Over a period of 30 years, 55 patients with mucoepidermoid carcinomas (MEC) of the salivary glands underwent surgical treatment. Reclassified TNM-stage (Hermanek et al., 1992) at the time of initial diagnosis varied (T0: 0, T1: 26, T2: 20, T3: 2, T4: 7; N0: 49, N1: 4, N2: 2; M0: 53, M1: 2). In 46% (n = 24), the history of symptoms ranged from 6 months to 2 years without any specificity of features. The therapy of choice is a radical ablative surgery of the primary tumour. The resection of the related lymphatic system has to be included in the therapeutic concept in patients suspected of having metastases of the regional lymph nodes. The prognosis is excellent in patients with a localized manifestation of the disease only. Our patients who died for reasons of tumour metastasis had all been classified as stage III or IV at the time initial diagnosis (n = 5). Distant metastases are rarely found even decades after surgical therapy (n = 1). This is why a long-term follow-up is recommended for patients with MEC of the salivary glands.",
keywords = "Adolescent, Adult, Aged, Carcinoma, Mucoepidermoid, Child, Female, Follow-Up Studies, Humans, Longitudinal Studies, Lymph Node Excision, Male, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Parotid Gland, Parotid Neoplasms, Prognosis, Salivary Gland Neoplasms, Salivary Glands, Survival Rate, Treatment Outcome",
author = "K Plambeck and Friedrich, {R E} and R Schmelzle",
year = "1996",
month = jun,
day = "1",
language = "English",
volume = "24",
pages = "133--9",
journal = "J CRANIO MAXILL SURG",
issn = "1010-5182",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Mucoepidermoid carcinoma of salivary gland origin

T2 - classification, clinical-pathological correlation, treatment results and long-term follow-up in 55 patients

AU - Plambeck, K

AU - Friedrich, R E

AU - Schmelzle, R

PY - 1996/6/1

Y1 - 1996/6/1

N2 - Over a period of 30 years, 55 patients with mucoepidermoid carcinomas (MEC) of the salivary glands underwent surgical treatment. Reclassified TNM-stage (Hermanek et al., 1992) at the time of initial diagnosis varied (T0: 0, T1: 26, T2: 20, T3: 2, T4: 7; N0: 49, N1: 4, N2: 2; M0: 53, M1: 2). In 46% (n = 24), the history of symptoms ranged from 6 months to 2 years without any specificity of features. The therapy of choice is a radical ablative surgery of the primary tumour. The resection of the related lymphatic system has to be included in the therapeutic concept in patients suspected of having metastases of the regional lymph nodes. The prognosis is excellent in patients with a localized manifestation of the disease only. Our patients who died for reasons of tumour metastasis had all been classified as stage III or IV at the time initial diagnosis (n = 5). Distant metastases are rarely found even decades after surgical therapy (n = 1). This is why a long-term follow-up is recommended for patients with MEC of the salivary glands.

AB - Over a period of 30 years, 55 patients with mucoepidermoid carcinomas (MEC) of the salivary glands underwent surgical treatment. Reclassified TNM-stage (Hermanek et al., 1992) at the time of initial diagnosis varied (T0: 0, T1: 26, T2: 20, T3: 2, T4: 7; N0: 49, N1: 4, N2: 2; M0: 53, M1: 2). In 46% (n = 24), the history of symptoms ranged from 6 months to 2 years without any specificity of features. The therapy of choice is a radical ablative surgery of the primary tumour. The resection of the related lymphatic system has to be included in the therapeutic concept in patients suspected of having metastases of the regional lymph nodes. The prognosis is excellent in patients with a localized manifestation of the disease only. Our patients who died for reasons of tumour metastasis had all been classified as stage III or IV at the time initial diagnosis (n = 5). Distant metastases are rarely found even decades after surgical therapy (n = 1). This is why a long-term follow-up is recommended for patients with MEC of the salivary glands.

KW - Adolescent

KW - Adult

KW - Aged

KW - Carcinoma, Mucoepidermoid

KW - Child

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Longitudinal Studies

KW - Lymph Node Excision

KW - Male

KW - Middle Aged

KW - Neoplasm Recurrence, Local

KW - Neoplasm Staging

KW - Parotid Gland

KW - Parotid Neoplasms

KW - Prognosis

KW - Salivary Gland Neoplasms

KW - Salivary Glands

KW - Survival Rate

KW - Treatment Outcome

M3 - SCORING: Journal article

C2 - 8842902

VL - 24

SP - 133

EP - 139

JO - J CRANIO MAXILL SURG

JF - J CRANIO MAXILL SURG

SN - 1010-5182

IS - 3

ER -