Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability.

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Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability. / Markowski, Dominique Nadine; Nimzyk, Rolf; Belge, Gazanfer; Löning, Thomas; Helmke, Burkhard Maria; Bullerdiek, Jörn.

In: MOL CYTOGENET, Vol. 6, No. 1, 1, 2013, p. 23.

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@article{f17c395bf9044753bdf604681d6fb2ec,
title = "Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability.",
abstract = "Deletions of the gene encoding mediator subcomplex 12 (MED12) in human smooth muscle tumors rank among the most frequent genomic alterations in human tumors at all. In a minority of these cases, small deletions are found. In an attempt to delineate key features of the deletions aimed at a better understanding of the molecular pathogenesis of uterine smooth muscle tumors we have analyzed 70 MED12 deletions including 46 cases from the literature and 24 own unpublished cases.",
author = "Markowski, {Dominique Nadine} and Rolf Nimzyk and Gazanfer Belge and Thomas L{\"o}ning and Helmke, {Burkhard Maria} and J{\"o}rn Bullerdiek",
year = "2013",
doi = "10.1186/1755-8166-6-23",
language = "English",
volume = "6",
pages = "23",
journal = "MOL CYTOGENET",
issn = "1755-8166",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability.

AU - Markowski, Dominique Nadine

AU - Nimzyk, Rolf

AU - Belge, Gazanfer

AU - Löning, Thomas

AU - Helmke, Burkhard Maria

AU - Bullerdiek, Jörn

PY - 2013

Y1 - 2013

N2 - Deletions of the gene encoding mediator subcomplex 12 (MED12) in human smooth muscle tumors rank among the most frequent genomic alterations in human tumors at all. In a minority of these cases, small deletions are found. In an attempt to delineate key features of the deletions aimed at a better understanding of the molecular pathogenesis of uterine smooth muscle tumors we have analyzed 70 MED12 deletions including 46 cases from the literature and 24 own unpublished cases.

AB - Deletions of the gene encoding mediator subcomplex 12 (MED12) in human smooth muscle tumors rank among the most frequent genomic alterations in human tumors at all. In a minority of these cases, small deletions are found. In an attempt to delineate key features of the deletions aimed at a better understanding of the molecular pathogenesis of uterine smooth muscle tumors we have analyzed 70 MED12 deletions including 46 cases from the literature and 24 own unpublished cases.

U2 - 10.1186/1755-8166-6-23

DO - 10.1186/1755-8166-6-23

M3 - SCORING: Journal article

VL - 6

SP - 23

JO - MOL CYTOGENET

JF - MOL CYTOGENET

SN - 1755-8166

IS - 1

M1 - 1

ER -