Research ExplorerPublicationsMolecular epidemiology of Mansonella species in Gabon

Molecular epidemiology of Mansonella species in Gabon

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Molecular epidemiology of Mansonella species in Gabon. / Sandri, Thaisa Lucas; Kreidenweiss, Andrea; Cavallo, Simon; Weber, David; Juhas, Sascha; Rodi, Miriam; Woldearegai, Tamirat Gebru; Gmeiner, Markus; Veletzky, Luzia; Ramharter, Michael; Tazemda-Kuitsouc, Gildas B; Matsiegui, Pierre Blaise; Mordmüller, Benjamin; Held, Jana.

In: J INFECT DIS, Vol. 223, No. 2, 03.02.2021, p. 287-296.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Sandri, TL, Kreidenweiss, A, Cavallo, S, Weber, D, Juhas, S, Rodi, M, Woldearegai, TG, Gmeiner, M, Veletzky, L, Ramharter, M, Tazemda-Kuitsouc, GB, Matsiegui, PB, Mordmüller, B & Held, J 2021, 'Molecular epidemiology of Mansonella species in Gabon', J INFECT DIS, vol. 223, no. 2, pp. 287-296. https://doi.org/10.1093/infdis/jiaa670

APA

Sandri, T. L., Kreidenweiss, A., Cavallo, S., Weber, D., Juhas, S., Rodi, M., Woldearegai, T. G., Gmeiner, M., Veletzky, L., Ramharter, M., Tazemda-Kuitsouc, G. B., Matsiegui, P. B., Mordmüller, B., & Held, J. (2021). Molecular epidemiology of Mansonella species in Gabon. J INFECT DIS, 223(2), 287-296. https://doi.org/10.1093/infdis/jiaa670

Vancouver

Sandri TL, Kreidenweiss A, Cavallo S, Weber D, Juhas S, Rodi M et al. Molecular epidemiology of Mansonella species in Gabon. J INFECT DIS. 2021 Feb 3;223(2):287-296. https://doi.org/10.1093/infdis/jiaa670

Bibtex

@article{647232b4aaa048ceaff90f7a45da60f9,
title = "Molecular epidemiology of Mansonella species in Gabon",
abstract = "Mansonella perstans, a filarial nematode, infects large populations in Africa and Latin America. Recently, a potential new species, Mansonella sp {"}DEUX,{"} was reported. Carriage of endosymbiotic Wolbachia opens treatment options for Mansonella infections. Within a cross-sectional study, we assessed the prevalence of filarial infections in 834 Gabonese individuals and the presence of the endosymbiont Wolbachia. Almost half of the participants (400/834 [48%]) were infected with filarial nematodes, with Mansonella sp {"}DEUX{"} being the most frequent (295/400 [74%]), followed by Loa loa (273/400 [68%]) and Mansonella perstans (82/400 [21%]). Being adult/elderly, male, and living in rural areas was associated with a higher risk of infection. Wolbachia carriage was confirmed in M. perstans and Mansonella sp {"}DEUX.{"} In silico analysis revealed that Mansonella sp {"}DEUX{"} is not detected with currently published M. perstans-specific assays. Mansonella infections are highly prevalent in Gabon and might have been underreported, likely also beyond Gabon.",
author = "Sandri, {Thaisa Lucas} and Andrea Kreidenweiss and Simon Cavallo and David Weber and Sascha Juhas and Miriam Rodi and Woldearegai, {Tamirat Gebru} and Markus Gmeiner and Luzia Veletzky and Michael Ramharter and Tazemda-Kuitsouc, {Gildas B} and Matsiegui, {Pierre Blaise} and Benjamin Mordm{\"u}ller and Jana Held",
note = "{\textcopyright} The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.",
year = "2021",
month = feb,
day = "3",
doi = "10.1093/infdis/jiaa670",
language = "English",
volume = "223",
pages = "287--296",
journal = "J INFECT DIS",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Molecular epidemiology of Mansonella species in Gabon

AU - Sandri, Thaisa Lucas

AU - Kreidenweiss, Andrea

AU - Cavallo, Simon

AU - Weber, David

AU - Juhas, Sascha

AU - Rodi, Miriam

AU - Woldearegai, Tamirat Gebru

AU - Gmeiner, Markus

AU - Veletzky, Luzia

AU - Ramharter, Michael

AU - Tazemda-Kuitsouc, Gildas B

AU - Matsiegui, Pierre Blaise

AU - Mordmüller, Benjamin

AU - Held, Jana

N1 - © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

PY - 2021/2/3

Y1 - 2021/2/3

N2 - Mansonella perstans, a filarial nematode, infects large populations in Africa and Latin America. Recently, a potential new species, Mansonella sp "DEUX," was reported. Carriage of endosymbiotic Wolbachia opens treatment options for Mansonella infections. Within a cross-sectional study, we assessed the prevalence of filarial infections in 834 Gabonese individuals and the presence of the endosymbiont Wolbachia. Almost half of the participants (400/834 [48%]) were infected with filarial nematodes, with Mansonella sp "DEUX" being the most frequent (295/400 [74%]), followed by Loa loa (273/400 [68%]) and Mansonella perstans (82/400 [21%]). Being adult/elderly, male, and living in rural areas was associated with a higher risk of infection. Wolbachia carriage was confirmed in M. perstans and Mansonella sp "DEUX." In silico analysis revealed that Mansonella sp "DEUX" is not detected with currently published M. perstans-specific assays. Mansonella infections are highly prevalent in Gabon and might have been underreported, likely also beyond Gabon.

AB - Mansonella perstans, a filarial nematode, infects large populations in Africa and Latin America. Recently, a potential new species, Mansonella sp "DEUX," was reported. Carriage of endosymbiotic Wolbachia opens treatment options for Mansonella infections. Within a cross-sectional study, we assessed the prevalence of filarial infections in 834 Gabonese individuals and the presence of the endosymbiont Wolbachia. Almost half of the participants (400/834 [48%]) were infected with filarial nematodes, with Mansonella sp "DEUX" being the most frequent (295/400 [74%]), followed by Loa loa (273/400 [68%]) and Mansonella perstans (82/400 [21%]). Being adult/elderly, male, and living in rural areas was associated with a higher risk of infection. Wolbachia carriage was confirmed in M. perstans and Mansonella sp "DEUX." In silico analysis revealed that Mansonella sp "DEUX" is not detected with currently published M. perstans-specific assays. Mansonella infections are highly prevalent in Gabon and might have been underreported, likely also beyond Gabon.

U2 - 10.1093/infdis/jiaa670

DO - 10.1093/infdis/jiaa670

M3 - SCORING: Journal article

C2 - 33099649

VL - 223

SP - 287

EP - 296

JO - J INFECT DIS

JF - J INFECT DIS

SN - 0022-1899

IS - 2

ER -