Moderne Diagnostik sexuell übertragbarer Infektionen
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Moderne Diagnostik sexuell übertragbarer Infektionen. / Brockmeyer, N H; Meyer, Thomas.
In: HAUTARZT, Vol. 67, No. 1, 01.2016, p. 16-22.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Moderne Diagnostik sexuell übertragbarer Infektionen
AU - Brockmeyer, N H
AU - Meyer, Thomas
PY - 2016/1
Y1 - 2016/1
N2 - Diagnosis of sexually transmitted diseases (STD) has significantly improved in recent years by the application of nucleic acid amplification tests (NAAT). In addition to detection of infectious agents, molecular methods were also used for characterization of pathogens (typing, genotypic resistance testing). In contrast to conventional Sanger sequencing of amplicons, new sequencing technologies (next generation sequencing) are able to identify resistant variants that represent only small minorities in a heterogeneous population. NAATs are also available as fully automated closed systems that can be run independently of centralized laboratories and will become increasingly important for point-of-care testing.
AB - Diagnosis of sexually transmitted diseases (STD) has significantly improved in recent years by the application of nucleic acid amplification tests (NAAT). In addition to detection of infectious agents, molecular methods were also used for characterization of pathogens (typing, genotypic resistance testing). In contrast to conventional Sanger sequencing of amplicons, new sequencing technologies (next generation sequencing) are able to identify resistant variants that represent only small minorities in a heterogeneous population. NAATs are also available as fully automated closed systems that can be run independently of centralized laboratories and will become increasingly important for point-of-care testing.
KW - Bacteria
KW - High-Throughput Nucleotide Sequencing
KW - Humans
KW - Point-of-Care Systems
KW - Sexually Transmitted Diseases, Bacterial
KW - Journal Article
KW - Review
U2 - 10.1007/s00105-015-3726-6
DO - 10.1007/s00105-015-3726-6
M3 - SCORING: Zeitschriftenaufsatz
C2 - 26646440
VL - 67
SP - 16
EP - 22
JO - HAUTARZT
JF - HAUTARZT
SN - 0017-8470
IS - 1
ER -