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Metformin after bariatric surgery--an acid problem.

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Metformin after bariatric surgery--an acid problem. / Aberle, Jens; Reining, Franziska; Dannheim, Viola; Flitsch, Joerg; Klinge, A; Mann, Oliver.

In: EXP CLIN ENDOCR DIAB, Vol. 120, No. 3, 3, 2012, p. 152-153.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Aberle, J, Reining, F, Dannheim, V, Flitsch, J, Klinge, A & Mann, O 2012, 'Metformin after bariatric surgery--an acid problem.', EXP CLIN ENDOCR DIAB, vol. 120, no. 3, 3, pp. 152-153. <http://www.ncbi.nlm.nih.gov/pubmed/21915819?dopt=Citation>

APA

Aberle, J., Reining, F., Dannheim, V., Flitsch, J., Klinge, A., & Mann, O. (2012). Metformin after bariatric surgery--an acid problem. EXP CLIN ENDOCR DIAB, 120(3), 152-153. [3]. http://www.ncbi.nlm.nih.gov/pubmed/21915819?dopt=Citation

Vancouver

Aberle J, Reining F, Dannheim V, Flitsch J, Klinge A, Mann O. Metformin after bariatric surgery--an acid problem. EXP CLIN ENDOCR DIAB. 2012;120(3):152-153. 3.

Bibtex

@article{5ae61ff8f9214fbb96920af05c897e73,
title = "Metformin after bariatric surgery--an acid problem.",
abstract = "Metformin is the oral drug of first choice in type 2 diabetes. Therefore a large number of patients undergoing bariatric surgery will be on Metformin treatment. However, use of Metformin has been associated with lactate acidosis. Weight loss following bariatric surgery is most pronounced during the first weeks after the operation and this creates a phase of negative energy balance with ketone body formation. To shed more light on this situation we measured ketone bodies in 90 patients 5 days-18 months after bariatric surgery. Ketone bodies were markedly elevated during the first 3-4 months. Metformin use should therefore be critically reconsidered after bariatric operations.",
keywords = "Adult, Humans, Male, Female, Middle Aged, Practice Guidelines as Topic, Follow-Up Studies, Time Factors, Combined Modality Therapy, Drug Administration Schedule, Acids/blood, *Bariatric Surgery/methods/rehabilitation, Diabetes Mellitus, Type 2/blood/complications/drug therapy, Hypoglycemic Agents/administration & dosage, Ketone Bodies/*blood, Metformin/*administration & dosage, Obesity/blood/complications/drug therapy/*surgery, Postoperative Care/*methods, Adult, Humans, Male, Female, Middle Aged, Practice Guidelines as Topic, Follow-Up Studies, Time Factors, Combined Modality Therapy, Drug Administration Schedule, Acids/blood, *Bariatric Surgery/methods/rehabilitation, Diabetes Mellitus, Type 2/blood/complications/drug therapy, Hypoglycemic Agents/administration & dosage, Ketone Bodies/*blood, Metformin/*administration & dosage, Obesity/blood/complications/drug therapy/*surgery, Postoperative Care/*methods",
author = "Jens Aberle and Franziska Reining and Viola Dannheim and Joerg Flitsch and A Klinge and Oliver Mann",
year = "2012",
language = "English",
volume = "120",
pages = "152--153",
journal = "EXP CLIN ENDOCR DIAB",
issn = "0947-7349",
publisher = "Georg Thieme Verlag KG",
number = "3",

}

RIS

TY - JOUR

T1 - Metformin after bariatric surgery--an acid problem.

AU - Aberle, Jens

AU - Reining, Franziska

AU - Dannheim, Viola

AU - Flitsch, Joerg

AU - Klinge, A

AU - Mann, Oliver

PY - 2012

Y1 - 2012

N2 - Metformin is the oral drug of first choice in type 2 diabetes. Therefore a large number of patients undergoing bariatric surgery will be on Metformin treatment. However, use of Metformin has been associated with lactate acidosis. Weight loss following bariatric surgery is most pronounced during the first weeks after the operation and this creates a phase of negative energy balance with ketone body formation. To shed more light on this situation we measured ketone bodies in 90 patients 5 days-18 months after bariatric surgery. Ketone bodies were markedly elevated during the first 3-4 months. Metformin use should therefore be critically reconsidered after bariatric operations.

AB - Metformin is the oral drug of first choice in type 2 diabetes. Therefore a large number of patients undergoing bariatric surgery will be on Metformin treatment. However, use of Metformin has been associated with lactate acidosis. Weight loss following bariatric surgery is most pronounced during the first weeks after the operation and this creates a phase of negative energy balance with ketone body formation. To shed more light on this situation we measured ketone bodies in 90 patients 5 days-18 months after bariatric surgery. Ketone bodies were markedly elevated during the first 3-4 months. Metformin use should therefore be critically reconsidered after bariatric operations.

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Practice Guidelines as Topic

KW - Follow-Up Studies

KW - Time Factors

KW - Combined Modality Therapy

KW - Drug Administration Schedule

KW - Acids/blood

KW - Bariatric Surgery/methods/rehabilitation

KW - Diabetes Mellitus, Type 2/blood/complications/drug therapy

KW - Hypoglycemic Agents/administration & dosage

KW - Ketone Bodies/blood

KW - Metformin/administration & dosage

KW - Obesity/blood/complications/drug therapy/surgery

KW - Postoperative Care/methods

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Practice Guidelines as Topic

KW - Follow-Up Studies

KW - Time Factors

KW - Combined Modality Therapy

KW - Drug Administration Schedule

KW - Acids/blood

KW - Bariatric Surgery/methods/rehabilitation

KW - Diabetes Mellitus, Type 2/blood/complications/drug therapy

KW - Hypoglycemic Agents/administration & dosage

KW - Ketone Bodies/blood

KW - Metformin/administration & dosage

KW - Obesity/blood/complications/drug therapy/surgery

KW - Postoperative Care/methods

M3 - SCORING: Journal article

VL - 120

SP - 152

EP - 153

JO - EXP CLIN ENDOCR DIAB

JF - EXP CLIN ENDOCR DIAB

SN - 0947-7349

IS - 3

M1 - 3

ER -