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Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation.

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Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation. / Karn, Thomas; Pusztai, Lajos; Ruckhäberle, Eugen; Liedtke, Cornelia; Müller, Volkmar; Schmidt, Marcus; Metzler, Dirk; Wang, Jing; Coombes, Kevin R; Gätje, Regine; Hanker, Lars; Solbach, Christine; Ahr, Andre; Holtrich, Uwe; Rody, Achim; Kaufmann, Manfred.

In: EUR J CANCER, Vol. 48, No. 1, 1, 2012, p. 12-23.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Karn, T, Pusztai, L, Ruckhäberle, E, Liedtke, C, Müller, V, Schmidt, M, Metzler, D, Wang, J, Coombes, KR, Gätje, R, Hanker, L, Solbach, C, Ahr, A, Holtrich, U, Rody, A & Kaufmann, M 2012, 'Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation.', EUR J CANCER, vol. 48, no. 1, 1, pp. 12-23. <http://www.ncbi.nlm.nih.gov/pubmed/21741824?dopt=Citation>

APA

Karn, T., Pusztai, L., Ruckhäberle, E., Liedtke, C., Müller, V., Schmidt, M., Metzler, D., Wang, J., Coombes, K. R., Gätje, R., Hanker, L., Solbach, C., Ahr, A., Holtrich, U., Rody, A., & Kaufmann, M. (2012). Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation. EUR J CANCER, 48(1), 12-23. [1]. http://www.ncbi.nlm.nih.gov/pubmed/21741824?dopt=Citation

Vancouver

Karn T, Pusztai L, Ruckhäberle E, Liedtke C, Müller V, Schmidt M et al. Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation. EUR J CANCER. 2012;48(1):12-23. 1.

Bibtex

@article{1bfda9a96f394d47a2482e5df08f81a5,
title = "Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation.",
abstract = "Molecular markers displaying bimodal expression distribution can reveal distinct disease subsets and may serve as prognostic or predictive markers or represent therapeutic targets. Oestrogen (ER) and human epidermal growth factor receptor 2 (HER2) receptors are strongly bimodally expressed genes in breast cancer.",
keywords = "Adult, Humans, Aged, Female, Middle Aged, Aged, 80 and over, Health Status Indicators, Algorithms, Gene Expression Regulation, Neoplastic, Gene Expression Profiling, Receptors, Estrogen/genetics/metabolism, Microarray Analysis, Immunotherapy/methods, Receptor, erbB-2/genetics/metabolism, Breast Neoplasms/*classification/diagnosis/genetics/*therapy, Cancer Vaccines/*therapeutic use, Carcinoma/*classification/diagnosis/genetics/*therapy, Melanoma-Specific Antigens/analysis/genetics/*physiology, Receptors, Progesterone/genetics/metabolism, Adult, Humans, Aged, Female, Middle Aged, Aged, 80 and over, Health Status Indicators, Algorithms, Gene Expression Regulation, Neoplastic, Gene Expression Profiling, Receptors, Estrogen/genetics/metabolism, Microarray Analysis, Immunotherapy/methods, Receptor, erbB-2/genetics/metabolism, Breast Neoplasms/*classification/diagnosis/genetics/*therapy, Cancer Vaccines/*therapeutic use, Carcinoma/*classification/diagnosis/genetics/*therapy, Melanoma-Specific Antigens/analysis/genetics/*physiology, Receptors, Progesterone/genetics/metabolism",
author = "Thomas Karn and Lajos Pusztai and Eugen Ruckh{\"a}berle and Cornelia Liedtke and Volkmar M{\"u}ller and Marcus Schmidt and Dirk Metzler and Jing Wang and Coombes, {Kevin R} and Regine G{\"a}tje and Lars Hanker and Christine Solbach and Andre Ahr and Uwe Holtrich and Achim Rody and Manfred Kaufmann",
year = "2012",
language = "English",
volume = "48",
pages = "12--23",
journal = "EUR J CANCER",
issn = "0959-8049",
publisher = "Elsevier Limited",
number = "1",

}

RIS

TY - JOUR

T1 - Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation.

AU - Karn, Thomas

AU - Pusztai, Lajos

AU - Ruckhäberle, Eugen

AU - Liedtke, Cornelia

AU - Müller, Volkmar

AU - Schmidt, Marcus

AU - Metzler, Dirk

AU - Wang, Jing

AU - Coombes, Kevin R

AU - Gätje, Regine

AU - Hanker, Lars

AU - Solbach, Christine

AU - Ahr, Andre

AU - Holtrich, Uwe

AU - Rody, Achim

AU - Kaufmann, Manfred

PY - 2012

Y1 - 2012

N2 - Molecular markers displaying bimodal expression distribution can reveal distinct disease subsets and may serve as prognostic or predictive markers or represent therapeutic targets. Oestrogen (ER) and human epidermal growth factor receptor 2 (HER2) receptors are strongly bimodally expressed genes in breast cancer.

AB - Molecular markers displaying bimodal expression distribution can reveal distinct disease subsets and may serve as prognostic or predictive markers or represent therapeutic targets. Oestrogen (ER) and human epidermal growth factor receptor 2 (HER2) receptors are strongly bimodally expressed genes in breast cancer.

KW - Adult

KW - Humans

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Health Status Indicators

KW - Algorithms

KW - Gene Expression Regulation, Neoplastic

KW - Gene Expression Profiling

KW - Receptors, Estrogen/genetics/metabolism

KW - Microarray Analysis

KW - Immunotherapy/methods

KW - Receptor, erbB-2/genetics/metabolism

KW - Breast Neoplasms/classification/diagnosis/genetics/therapy

KW - Cancer Vaccines/therapeutic use

KW - Carcinoma/classification/diagnosis/genetics/therapy

KW - Melanoma-Specific Antigens/analysis/genetics/physiology

KW - Receptors, Progesterone/genetics/metabolism

KW - Adult

KW - Humans

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Health Status Indicators

KW - Algorithms

KW - Gene Expression Regulation, Neoplastic

KW - Gene Expression Profiling

KW - Receptors, Estrogen/genetics/metabolism

KW - Microarray Analysis

KW - Immunotherapy/methods

KW - Receptor, erbB-2/genetics/metabolism

KW - Breast Neoplasms/classification/diagnosis/genetics/therapy

KW - Cancer Vaccines/therapeutic use

KW - Carcinoma/classification/diagnosis/genetics/therapy

KW - Melanoma-Specific Antigens/analysis/genetics/physiology

KW - Receptors, Progesterone/genetics/metabolism

M3 - SCORING: Journal article

VL - 48

SP - 12

EP - 23

JO - EUR J CANCER

JF - EUR J CANCER

SN - 0959-8049

IS - 1

M1 - 1

ER -