Measurement of epithelial thickness within the oral cavity using optical coherence tomography

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Measurement of epithelial thickness within the oral cavity using optical coherence tomography. / Prestin, Sven; Rothschild, Sacha I; Betz, Christian Stephan; Kraft, Marcel.

In: HEAD NECK-J SCI SPEC, Vol. 34, No. 12, 12.2012, p. 1777-81.

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@article{2270f3a990c74eb3b1bcfccb58574476,
title = "Measurement of epithelial thickness within the oral cavity using optical coherence tomography",
abstract = "BACKGROUND: The purpose of the present study was to determine normal values of epithelial thickness within the oral cavity by using optical coherence tomography (OCT).METHODS: In a total of 143 healthy test persons, epithelial thickness of the oral mucosa was determined with the help of OCT separately for each side at 7 different locations. Special attention was directed to those sites having the highest incidence for the development of dysplasias and carcinomas.RESULTS: The epithelium demonstrated a varying thickness depending on its location within the oral cavity. The highest values were found in the region of the buccal mucosa (294 μm) and the hard palate (239 μm), whereas the thinnest epithelium was measured at the floor of the mouth (99 μm).CONCLUSION: Our data serve as reference values for detecting oral malignancy and determining the approximate grade of dysplasia. In this circumstance, a differentiated view of the different regions is important due to a variation in thickness of the epithelium within the oral cavity.",
keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Epithelium, Female, Humans, Male, Middle Aged, Mouth Mucosa, Mouth Neoplasms, Palate, Hard, Precancerous Conditions, Prospective Studies, Reference Values, Tomography, Optical Coherence, Young Adult, Journal Article",
author = "Sven Prestin and Rothschild, {Sacha I} and Betz, {Christian Stephan} and Marcel Kraft",
note = "Copyright {\textcopyright} 2012 Wiley Periodicals, Inc.",
year = "2012",
month = dec,
doi = "10.1002/hed.22007",
language = "English",
volume = "34",
pages = "1777--81",
journal = "HEAD NECK-J SCI SPEC",
issn = "1043-3074",
publisher = "John Wiley and Sons Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - Measurement of epithelial thickness within the oral cavity using optical coherence tomography

AU - Prestin, Sven

AU - Rothschild, Sacha I

AU - Betz, Christian Stephan

AU - Kraft, Marcel

N1 - Copyright © 2012 Wiley Periodicals, Inc.

PY - 2012/12

Y1 - 2012/12

N2 - BACKGROUND: The purpose of the present study was to determine normal values of epithelial thickness within the oral cavity by using optical coherence tomography (OCT).METHODS: In a total of 143 healthy test persons, epithelial thickness of the oral mucosa was determined with the help of OCT separately for each side at 7 different locations. Special attention was directed to those sites having the highest incidence for the development of dysplasias and carcinomas.RESULTS: The epithelium demonstrated a varying thickness depending on its location within the oral cavity. The highest values were found in the region of the buccal mucosa (294 μm) and the hard palate (239 μm), whereas the thinnest epithelium was measured at the floor of the mouth (99 μm).CONCLUSION: Our data serve as reference values for detecting oral malignancy and determining the approximate grade of dysplasia. In this circumstance, a differentiated view of the different regions is important due to a variation in thickness of the epithelium within the oral cavity.

AB - BACKGROUND: The purpose of the present study was to determine normal values of epithelial thickness within the oral cavity by using optical coherence tomography (OCT).METHODS: In a total of 143 healthy test persons, epithelial thickness of the oral mucosa was determined with the help of OCT separately for each side at 7 different locations. Special attention was directed to those sites having the highest incidence for the development of dysplasias and carcinomas.RESULTS: The epithelium demonstrated a varying thickness depending on its location within the oral cavity. The highest values were found in the region of the buccal mucosa (294 μm) and the hard palate (239 μm), whereas the thinnest epithelium was measured at the floor of the mouth (99 μm).CONCLUSION: Our data serve as reference values for detecting oral malignancy and determining the approximate grade of dysplasia. In this circumstance, a differentiated view of the different regions is important due to a variation in thickness of the epithelium within the oral cavity.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Epithelium

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Mouth Mucosa

KW - Mouth Neoplasms

KW - Palate, Hard

KW - Precancerous Conditions

KW - Prospective Studies

KW - Reference Values

KW - Tomography, Optical Coherence

KW - Young Adult

KW - Journal Article

U2 - 10.1002/hed.22007

DO - 10.1002/hed.22007

M3 - SCORING: Journal article

C2 - 22318761

VL - 34

SP - 1777

EP - 1781

JO - HEAD NECK-J SCI SPEC

JF - HEAD NECK-J SCI SPEC

SN - 1043-3074

IS - 12

ER -