Measurement of epithelial thickness within the oral cavity using optical coherence tomography
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Measurement of epithelial thickness within the oral cavity using optical coherence tomography. / Prestin, Sven; Rothschild, Sacha I; Betz, Christian Stephan; Kraft, Marcel.
in: HEAD NECK-J SCI SPEC, Jahrgang 34, Nr. 12, 12.2012, S. 1777-81.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Measurement of epithelial thickness within the oral cavity using optical coherence tomography
AU - Prestin, Sven
AU - Rothschild, Sacha I
AU - Betz, Christian Stephan
AU - Kraft, Marcel
N1 - Copyright © 2012 Wiley Periodicals, Inc.
PY - 2012/12
Y1 - 2012/12
N2 - BACKGROUND: The purpose of the present study was to determine normal values of epithelial thickness within the oral cavity by using optical coherence tomography (OCT).METHODS: In a total of 143 healthy test persons, epithelial thickness of the oral mucosa was determined with the help of OCT separately for each side at 7 different locations. Special attention was directed to those sites having the highest incidence for the development of dysplasias and carcinomas.RESULTS: The epithelium demonstrated a varying thickness depending on its location within the oral cavity. The highest values were found in the region of the buccal mucosa (294 μm) and the hard palate (239 μm), whereas the thinnest epithelium was measured at the floor of the mouth (99 μm).CONCLUSION: Our data serve as reference values for detecting oral malignancy and determining the approximate grade of dysplasia. In this circumstance, a differentiated view of the different regions is important due to a variation in thickness of the epithelium within the oral cavity.
AB - BACKGROUND: The purpose of the present study was to determine normal values of epithelial thickness within the oral cavity by using optical coherence tomography (OCT).METHODS: In a total of 143 healthy test persons, epithelial thickness of the oral mucosa was determined with the help of OCT separately for each side at 7 different locations. Special attention was directed to those sites having the highest incidence for the development of dysplasias and carcinomas.RESULTS: The epithelium demonstrated a varying thickness depending on its location within the oral cavity. The highest values were found in the region of the buccal mucosa (294 μm) and the hard palate (239 μm), whereas the thinnest epithelium was measured at the floor of the mouth (99 μm).CONCLUSION: Our data serve as reference values for detecting oral malignancy and determining the approximate grade of dysplasia. In this circumstance, a differentiated view of the different regions is important due to a variation in thickness of the epithelium within the oral cavity.
KW - Adolescent
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Epithelium
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Mouth Mucosa
KW - Mouth Neoplasms
KW - Palate, Hard
KW - Precancerous Conditions
KW - Prospective Studies
KW - Reference Values
KW - Tomography, Optical Coherence
KW - Young Adult
KW - Journal Article
U2 - 10.1002/hed.22007
DO - 10.1002/hed.22007
M3 - SCORING: Journal article
C2 - 22318761
VL - 34
SP - 1777
EP - 1781
JO - HEAD NECK-J SCI SPEC
JF - HEAD NECK-J SCI SPEC
SN - 1043-3074
IS - 12
ER -