Research ExplorerPublicationsManagement of hepatic encephalopathy in Germany

Management of hepatic encephalopathy in Germany

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Management of hepatic encephalopathy in Germany : a survey among physicians. / Labenz, Christian; Adarkwah, Charles C; Wörns, Marcus-Alexander; Miehlke, Stephan; Hofmann, Wolf P; Buggisch, Peter; Galle, Peter R; Frieling, Thomas; Labenz, Joachim.

In: Z GASTROENTEROL, Vol. 58, No. 1, 01.2020, p. 49-56.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Labenz, C, Adarkwah, CC, Wörns, M-A, Miehlke, S, Hofmann, WP, Buggisch, P, Galle, PR, Frieling, T & Labenz, J 2020, 'Management of hepatic encephalopathy in Germany: a survey among physicians', Z GASTROENTEROL, vol. 58, no. 1, pp. 49-56. https://doi.org/10.1055/a-1010-6974

APA

Labenz, C., Adarkwah, C. C., Wörns, M-A., Miehlke, S., Hofmann, W. P., Buggisch, P., Galle, P. R., Frieling, T., & Labenz, J. (2020). Management of hepatic encephalopathy in Germany: a survey among physicians. Z GASTROENTEROL, 58(1), 49-56. https://doi.org/10.1055/a-1010-6974

Vancouver

Labenz C, Adarkwah CC, Wörns M-A, Miehlke S, Hofmann WP, Buggisch P et al. Management of hepatic encephalopathy in Germany: a survey among physicians. Z GASTROENTEROL. 2020 Jan;58(1):49-56. https://doi.org/10.1055/a-1010-6974

Bibtex

@article{b74c346120784e759285f5782b5944e7,
title = "Management of hepatic encephalopathy in Germany: a survey among physicians",
abstract = "BACKGROUND:  Hepatic encephalopathy (HE) is a severe complication of liver cirrhosis with impairment of quality of life and prognosis. Management patterns among physicians have not been investigated yet.METHODS:  A questionnaire containing 17 questions was sent out to 1468 gastroenterologists and 120 general practitioners (GPs). It included questions regarding diagnostic, therapeutic, and management strategies used in patients with overt HE (OHE) and covert HE (CHE).RESULTS:  The response rate was 12 % (n = 172) for gastroenterologists and 45 % (n = 54) for GPs. Of gastroenterologists, 26.7 % examine patients with an initial diagnosis of liver cirrhosis regarding HE. Gastroenterologists favored a combination of different testing strategies (27.9 %) and clinical examination (23.0 %), while the biggest part of the GPs use clinical examination (55.3 %); 63.7 % of gastroenterologists and 28.3 % of GPs give correct nutritional advices to patients with HE. Treatment strategies for acute bouts of OHE and secondary prophylaxis varied widely in both groups. Preferred medication was lactulose followed by rifaximin or a combination therapy. More than half of the GPs (53.7 %) were not familiar with minimal HE (MHE). About one-third of both groups never tried to diagnose MHE.CONCLUSION:  Our data strongly indicate that management of HE is very heterogeneous among gastroenterologists as well as selected GPs working in Germany and not driven by evidence-based international guidelines. Thus, the national guideline is more than welcome.",
keywords = "Disease Management, Gastroenterologists, Gastrointestinal Agents/therapeutic use, General Practitioners, Germany, Hepatic Encephalopathy/diagnosis, Humans, Lactulose/therapeutic use, Liver Cirrhosis/complications, Practice Patterns, Physicians'/statistics & numerical data, Quality of Life, Rifaximin/therapeutic use, Secondary Prevention/methods, Surveys and Questionnaires",
author = "Christian Labenz and Adarkwah, {Charles C} and Marcus-Alexander W{\"o}rns and Stephan Miehlke and Hofmann, {Wolf P} and Peter Buggisch and Galle, {Peter R} and Thomas Frieling and Joachim Labenz",
note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",
year = "2020",
month = jan,
doi = "10.1055/a-1010-6974",
language = "English",
volume = "58",
pages = "49--56",
journal = "Z GASTROENTEROL",
issn = "0044-2771",
publisher = "Karl Demeter Verlag GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Management of hepatic encephalopathy in Germany

T2 - a survey among physicians

AU - Labenz, Christian

AU - Adarkwah, Charles C

AU - Wörns, Marcus-Alexander

AU - Miehlke, Stephan

AU - Hofmann, Wolf P

AU - Buggisch, Peter

AU - Galle, Peter R

AU - Frieling, Thomas

AU - Labenz, Joachim

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2020/1

Y1 - 2020/1

N2 - BACKGROUND:  Hepatic encephalopathy (HE) is a severe complication of liver cirrhosis with impairment of quality of life and prognosis. Management patterns among physicians have not been investigated yet.METHODS:  A questionnaire containing 17 questions was sent out to 1468 gastroenterologists and 120 general practitioners (GPs). It included questions regarding diagnostic, therapeutic, and management strategies used in patients with overt HE (OHE) and covert HE (CHE).RESULTS:  The response rate was 12 % (n = 172) for gastroenterologists and 45 % (n = 54) for GPs. Of gastroenterologists, 26.7 % examine patients with an initial diagnosis of liver cirrhosis regarding HE. Gastroenterologists favored a combination of different testing strategies (27.9 %) and clinical examination (23.0 %), while the biggest part of the GPs use clinical examination (55.3 %); 63.7 % of gastroenterologists and 28.3 % of GPs give correct nutritional advices to patients with HE. Treatment strategies for acute bouts of OHE and secondary prophylaxis varied widely in both groups. Preferred medication was lactulose followed by rifaximin or a combination therapy. More than half of the GPs (53.7 %) were not familiar with minimal HE (MHE). About one-third of both groups never tried to diagnose MHE.CONCLUSION:  Our data strongly indicate that management of HE is very heterogeneous among gastroenterologists as well as selected GPs working in Germany and not driven by evidence-based international guidelines. Thus, the national guideline is more than welcome.

AB - BACKGROUND:  Hepatic encephalopathy (HE) is a severe complication of liver cirrhosis with impairment of quality of life and prognosis. Management patterns among physicians have not been investigated yet.METHODS:  A questionnaire containing 17 questions was sent out to 1468 gastroenterologists and 120 general practitioners (GPs). It included questions regarding diagnostic, therapeutic, and management strategies used in patients with overt HE (OHE) and covert HE (CHE).RESULTS:  The response rate was 12 % (n = 172) for gastroenterologists and 45 % (n = 54) for GPs. Of gastroenterologists, 26.7 % examine patients with an initial diagnosis of liver cirrhosis regarding HE. Gastroenterologists favored a combination of different testing strategies (27.9 %) and clinical examination (23.0 %), while the biggest part of the GPs use clinical examination (55.3 %); 63.7 % of gastroenterologists and 28.3 % of GPs give correct nutritional advices to patients with HE. Treatment strategies for acute bouts of OHE and secondary prophylaxis varied widely in both groups. Preferred medication was lactulose followed by rifaximin or a combination therapy. More than half of the GPs (53.7 %) were not familiar with minimal HE (MHE). About one-third of both groups never tried to diagnose MHE.CONCLUSION:  Our data strongly indicate that management of HE is very heterogeneous among gastroenterologists as well as selected GPs working in Germany and not driven by evidence-based international guidelines. Thus, the national guideline is more than welcome.

KW - Disease Management

KW - Gastroenterologists

KW - Gastrointestinal Agents/therapeutic use

KW - General Practitioners

KW - Germany

KW - Hepatic Encephalopathy/diagnosis

KW - Humans

KW - Lactulose/therapeutic use

KW - Liver Cirrhosis/complications

KW - Practice Patterns, Physicians'/statistics & numerical data

KW - Quality of Life

KW - Rifaximin/therapeutic use

KW - Secondary Prevention/methods

KW - Surveys and Questionnaires

U2 - 10.1055/a-1010-6974

DO - 10.1055/a-1010-6974

M3 - SCORING: Journal article

C2 - 31931540

VL - 58

SP - 49

EP - 56

JO - Z GASTROENTEROL

JF - Z GASTROENTEROL

SN - 0044-2771

IS - 1

ER -