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Lynx web services for annotations and systems analysis of multi-gene disorders

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Lynx web services for annotations and systems analysis of multi-gene disorders. / Sulakhe, Dinanath; Taylor, Andrew; Balasubramanian, Sandhya; Feng, Bo; Xie, Bingqing; Börnigen, Daniela; Dave, Utpal J; Foster, Ian T; Gilliam, T Conrad; Maltsev, Natalia.

In: NUCLEIC ACIDS RES, Vol. 42, No. Web Server issue, 07.2014, p. W473-477.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Sulakhe, D, Taylor, A, Balasubramanian, S, Feng, B, Xie, B, Börnigen, D, Dave, UJ, Foster, IT, Gilliam, TC & Maltsev, N 2014, 'Lynx web services for annotations and systems analysis of multi-gene disorders', NUCLEIC ACIDS RES, vol. 42, no. Web Server issue, pp. W473-477. https://doi.org/10.1093/nar/gku517

APA

Sulakhe, D., Taylor, A., Balasubramanian, S., Feng, B., Xie, B., Börnigen, D., Dave, U. J., Foster, I. T., Gilliam, T. C., & Maltsev, N. (2014). Lynx web services for annotations and systems analysis of multi-gene disorders. NUCLEIC ACIDS RES, 42(Web Server issue), W473-477. https://doi.org/10.1093/nar/gku517

Vancouver

Sulakhe D, Taylor A, Balasubramanian S, Feng B, Xie B, Börnigen D et al. Lynx web services for annotations and systems analysis of multi-gene disorders. NUCLEIC ACIDS RES. 2014 Jul;42(Web Server issue):W473-477. https://doi.org/10.1093/nar/gku517

Bibtex

@article{7395d8920e844fc1911a2dffadd2e9f0,
title = "Lynx web services for annotations and systems analysis of multi-gene disorders",
abstract = "Lynx is a web-based integrated systems biology platform that supports annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human phenotypes and disorders of interest. Lynx has integrated multiple classes of biomedical data (genomic, proteomic, pathways, phenotypic, toxicogenomic, contextual and others) from various public databases as well as manually curated data from our group and collaborators (LynxKB). Lynx provides tools for gene list enrichment analysis using multiple functional annotations and network-based gene prioritization. Lynx provides access to the integrated database and the analytical tools via REST based Web Services (http://lynx.ci.uchicago.edu/webservices.html). This comprises data retrieval services for specific functional annotations, services to search across the complete LynxKB (powered by Lucene), and services to access the analytical tools built within the Lynx platform.",
keywords = "Databases, Factual, Genes, Genetic Diseases, Inborn, Humans, Internet, Knowledge Bases, Software, Systems Biology, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't",
author = "Dinanath Sulakhe and Andrew Taylor and Sandhya Balasubramanian and Bo Feng and Bingqing Xie and Daniela B{\"o}rnigen and Dave, {Utpal J} and Foster, {Ian T} and Gilliam, {T Conrad} and Natalia Maltsev",
note = "{\textcopyright} The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.",
year = "2014",
month = jul,
doi = "10.1093/nar/gku517",
language = "English",
volume = "42",
pages = "W473--477",
journal = "NUCLEIC ACIDS RES",
issn = "0305-1048",
publisher = "Oxford University Press",
number = "Web Server issue",

}

RIS

TY - JOUR

T1 - Lynx web services for annotations and systems analysis of multi-gene disorders

AU - Sulakhe, Dinanath

AU - Taylor, Andrew

AU - Balasubramanian, Sandhya

AU - Feng, Bo

AU - Xie, Bingqing

AU - Börnigen, Daniela

AU - Dave, Utpal J

AU - Foster, Ian T

AU - Gilliam, T Conrad

AU - Maltsev, Natalia

N1 - © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

PY - 2014/7

Y1 - 2014/7

N2 - Lynx is a web-based integrated systems biology platform that supports annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human phenotypes and disorders of interest. Lynx has integrated multiple classes of biomedical data (genomic, proteomic, pathways, phenotypic, toxicogenomic, contextual and others) from various public databases as well as manually curated data from our group and collaborators (LynxKB). Lynx provides tools for gene list enrichment analysis using multiple functional annotations and network-based gene prioritization. Lynx provides access to the integrated database and the analytical tools via REST based Web Services (http://lynx.ci.uchicago.edu/webservices.html). This comprises data retrieval services for specific functional annotations, services to search across the complete LynxKB (powered by Lucene), and services to access the analytical tools built within the Lynx platform.

AB - Lynx is a web-based integrated systems biology platform that supports annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human phenotypes and disorders of interest. Lynx has integrated multiple classes of biomedical data (genomic, proteomic, pathways, phenotypic, toxicogenomic, contextual and others) from various public databases as well as manually curated data from our group and collaborators (LynxKB). Lynx provides tools for gene list enrichment analysis using multiple functional annotations and network-based gene prioritization. Lynx provides access to the integrated database and the analytical tools via REST based Web Services (http://lynx.ci.uchicago.edu/webservices.html). This comprises data retrieval services for specific functional annotations, services to search across the complete LynxKB (powered by Lucene), and services to access the analytical tools built within the Lynx platform.

KW - Databases, Factual

KW - Genes

KW - Genetic Diseases, Inborn

KW - Humans

KW - Internet

KW - Knowledge Bases

KW - Software

KW - Systems Biology

KW - Journal Article

KW - Research Support, N.I.H., Extramural

KW - Research Support, Non-U.S. Gov't

U2 - 10.1093/nar/gku517

DO - 10.1093/nar/gku517

M3 - SCORING: Journal article

C2 - 24948611

VL - 42

SP - W473-477

JO - NUCLEIC ACIDS RES

JF - NUCLEIC ACIDS RES

SN - 0305-1048

IS - Web Server issue

ER -