Research ExplorerPublicationsLong-term survival of an infant with an atypical teratoid/rh...

Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report

Standard

Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report. / Arnhold, Viktor; Oyen, Florian; Schneppenheim, Reinhard; Haberl, Hannes; Koch, Arend; Frühwald, Michael C; Hernáiz Driever, Pablo.

In: CHILD NERV SYST, Vol. 32, No. 6, 08.01.2016, p. 1157-61.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Arnhold, V, Oyen, F, Schneppenheim, R, Haberl, H, Koch, A, Frühwald, MC & Hernáiz Driever, P 2016, 'Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report', CHILD NERV SYST, vol. 32, no. 6, pp. 1157-61. https://doi.org/10.1007/s00381-015-2999-5

APA

Arnhold, V., Oyen, F., Schneppenheim, R., Haberl, H., Koch, A., Frühwald, M. C., & Hernáiz Driever, P. (2016). Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report. CHILD NERV SYST, 32(6), 1157-61. https://doi.org/10.1007/s00381-015-2999-5

Vancouver

Arnhold V, Oyen F, Schneppenheim R, Haberl H, Koch A, Frühwald MC et al. Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report. CHILD NERV SYST. 2016 Jan 8;32(6):1157-61. https://doi.org/10.1007/s00381-015-2999-5

Bibtex

@article{9d4867dea2c34472b8531f2719a3e127,
title = "Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report",
abstract = "INTRODUCTION: Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive embryonal tumor of the central nervous system with a generally dismal prognosis, especially in patients younger than 12 months.DISCUSSION: We here describe the unusual case of an infant with AT/RT with long-term survival despite low-cumulative dose chemotherapy after subtotal resection. Due to a poor neurological situation and an unfavorable oncological prognosis, therapy was halted after two partial surgical resections and four of the nine chemotherapy courses recommended by the European Rhabdoid Registry, without the patient receiving either radiotherapy or high-dose chemotherapy. The patient is alive without evidence of disease 52 months after diagnosis.CONCLUSION: This case report highlights that independent prognostic factors are urgently needed for optimizing treatment stratification and preventing overtreatment.",
author = "Viktor Arnhold and Florian Oyen and Reinhard Schneppenheim and Hannes Haberl and Arend Koch and Fr{\"u}hwald, {Michael C} and {Hern{\'a}iz Driever}, Pablo",
year = "2016",
month = jan,
day = "8",
doi = "10.1007/s00381-015-2999-5",
language = "English",
volume = "32",
pages = "1157--61",
journal = "CHILD NERV SYST",
issn = "0256-7040",
publisher = "Springer",
number = "6",

}

RIS

TY - JOUR

T1 - Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report

AU - Arnhold, Viktor

AU - Oyen, Florian

AU - Schneppenheim, Reinhard

AU - Haberl, Hannes

AU - Koch, Arend

AU - Frühwald, Michael C

AU - Hernáiz Driever, Pablo

PY - 2016/1/8

Y1 - 2016/1/8

N2 - INTRODUCTION: Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive embryonal tumor of the central nervous system with a generally dismal prognosis, especially in patients younger than 12 months.DISCUSSION: We here describe the unusual case of an infant with AT/RT with long-term survival despite low-cumulative dose chemotherapy after subtotal resection. Due to a poor neurological situation and an unfavorable oncological prognosis, therapy was halted after two partial surgical resections and four of the nine chemotherapy courses recommended by the European Rhabdoid Registry, without the patient receiving either radiotherapy or high-dose chemotherapy. The patient is alive without evidence of disease 52 months after diagnosis.CONCLUSION: This case report highlights that independent prognostic factors are urgently needed for optimizing treatment stratification and preventing overtreatment.

AB - INTRODUCTION: Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive embryonal tumor of the central nervous system with a generally dismal prognosis, especially in patients younger than 12 months.DISCUSSION: We here describe the unusual case of an infant with AT/RT with long-term survival despite low-cumulative dose chemotherapy after subtotal resection. Due to a poor neurological situation and an unfavorable oncological prognosis, therapy was halted after two partial surgical resections and four of the nine chemotherapy courses recommended by the European Rhabdoid Registry, without the patient receiving either radiotherapy or high-dose chemotherapy. The patient is alive without evidence of disease 52 months after diagnosis.CONCLUSION: This case report highlights that independent prognostic factors are urgently needed for optimizing treatment stratification and preventing overtreatment.

U2 - 10.1007/s00381-015-2999-5

DO - 10.1007/s00381-015-2999-5

M3 - SCORING: Journal article

C2 - 26747622

VL - 32

SP - 1157

EP - 1161

JO - CHILD NERV SYST

JF - CHILD NERV SYST

SN - 0256-7040

IS - 6

ER -