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Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study.

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Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study. / Goralczyk, Armin D; Abu-Ajaj, Wijdan; Tsui, Tung Yu; Bauer, Martin; Lorf, Thomas; Ramadori, Giuliano; Obed, Aiman.

In: TRANSPL INT, Vol. 24, No. 11, 11, 2011, p. 1068-1074.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Goralczyk, AD, Abu-Ajaj, W, Tsui, TY, Bauer, M, Lorf, T, Ramadori, G & Obed, A 2011, 'Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study.', TRANSPL INT, vol. 24, no. 11, 11, pp. 1068-1074. <http://www.ncbi.nlm.nih.gov/pubmed/21883503?dopt=Citation>

APA

Goralczyk, A. D., Abu-Ajaj, W., Tsui, T. Y., Bauer, M., Lorf, T., Ramadori, G., & Obed, A. (2011). Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study. TRANSPL INT, 24(11), 1068-1074. [11]. http://www.ncbi.nlm.nih.gov/pubmed/21883503?dopt=Citation

Vancouver

Goralczyk AD, Abu-Ajaj W, Tsui TY, Bauer M, Lorf T, Ramadori G et al. Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study. TRANSPL INT. 2011;24(11):1068-1074. 11.

Bibtex

@article{dd450d525eb44e96967b0a2444bd6fa1,
title = "Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study.",
abstract = "Patients with chronic liver disease are at high risk for severe infection because of increased bacterial translocation and immune suppression associated with liver dysfunction. Patients presenting with severe pneumonia and acute decompensation of cirrhosis are generally not considered for liver transplantation because it is unknown if these patients can recover from infection while under immunosuppression. We performed an observational study where patients with cirrhosis of the liver remained on the waiting list, although suffering from active pneumonia. Nine patients were included, but only six patients improved under goal-directed therapy and subsequently underwent liver transplantation. All six patients recovered quickly from infection; five patients recovered without sequelae and one patient died because of late complications. We propose that in patients with chronic liver disease and active pneumonia transplantation is a treatment option that should not hastily be abandoned.",
keywords = "Humans, Male, Female, Middle Aged, Treatment Outcome, Waiting Lists, *Liver Transplantation, Liver Cirrhosis/*surgery, Pneumonia/*surgery, Humans, Male, Female, Middle Aged, Treatment Outcome, Waiting Lists, *Liver Transplantation, Liver Cirrhosis/*surgery, Pneumonia/*surgery",
author = "Goralczyk, {Armin D} and Wijdan Abu-Ajaj and Tsui, {Tung Yu} and Martin Bauer and Thomas Lorf and Giuliano Ramadori and Aiman Obed",
year = "2011",
language = "English",
volume = "24",
pages = "1068--1074",
journal = "TRANSPL INT",
issn = "0934-0874",
publisher = "Wiley-Blackwell",
number = "11",

}

RIS

TY - JOUR

T1 - Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study.

AU - Goralczyk, Armin D

AU - Abu-Ajaj, Wijdan

AU - Tsui, Tung Yu

AU - Bauer, Martin

AU - Lorf, Thomas

AU - Ramadori, Giuliano

AU - Obed, Aiman

PY - 2011

Y1 - 2011

N2 - Patients with chronic liver disease are at high risk for severe infection because of increased bacterial translocation and immune suppression associated with liver dysfunction. Patients presenting with severe pneumonia and acute decompensation of cirrhosis are generally not considered for liver transplantation because it is unknown if these patients can recover from infection while under immunosuppression. We performed an observational study where patients with cirrhosis of the liver remained on the waiting list, although suffering from active pneumonia. Nine patients were included, but only six patients improved under goal-directed therapy and subsequently underwent liver transplantation. All six patients recovered quickly from infection; five patients recovered without sequelae and one patient died because of late complications. We propose that in patients with chronic liver disease and active pneumonia transplantation is a treatment option that should not hastily be abandoned.

AB - Patients with chronic liver disease are at high risk for severe infection because of increased bacterial translocation and immune suppression associated with liver dysfunction. Patients presenting with severe pneumonia and acute decompensation of cirrhosis are generally not considered for liver transplantation because it is unknown if these patients can recover from infection while under immunosuppression. We performed an observational study where patients with cirrhosis of the liver remained on the waiting list, although suffering from active pneumonia. Nine patients were included, but only six patients improved under goal-directed therapy and subsequently underwent liver transplantation. All six patients recovered quickly from infection; five patients recovered without sequelae and one patient died because of late complications. We propose that in patients with chronic liver disease and active pneumonia transplantation is a treatment option that should not hastily be abandoned.

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Treatment Outcome

KW - Waiting Lists

KW - Liver Transplantation

KW - Liver Cirrhosis/surgery

KW - Pneumonia/surgery

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Treatment Outcome

KW - Waiting Lists

KW - Liver Transplantation

KW - Liver Cirrhosis/surgery

KW - Pneumonia/surgery

M3 - SCORING: Journal article

VL - 24

SP - 1068

EP - 1074

JO - TRANSPL INT

JF - TRANSPL INT

SN - 0934-0874

IS - 11

M1 - 11

ER -