Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study.
Standard
Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study. / Goralczyk, Armin D; Abu-Ajaj, Wijdan; Tsui, Tung Yu; Bauer, Martin; Lorf, Thomas; Ramadori, Giuliano; Obed, Aiman.
in: TRANSPL INT, Jahrgang 24, Nr. 11, 11, 2011, S. 1068-1074.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Liver transplantation in patients with liver cirrhosis and active pneumonia: an observational study.
AU - Goralczyk, Armin D
AU - Abu-Ajaj, Wijdan
AU - Tsui, Tung Yu
AU - Bauer, Martin
AU - Lorf, Thomas
AU - Ramadori, Giuliano
AU - Obed, Aiman
PY - 2011
Y1 - 2011
N2 - Patients with chronic liver disease are at high risk for severe infection because of increased bacterial translocation and immune suppression associated with liver dysfunction. Patients presenting with severe pneumonia and acute decompensation of cirrhosis are generally not considered for liver transplantation because it is unknown if these patients can recover from infection while under immunosuppression. We performed an observational study where patients with cirrhosis of the liver remained on the waiting list, although suffering from active pneumonia. Nine patients were included, but only six patients improved under goal-directed therapy and subsequently underwent liver transplantation. All six patients recovered quickly from infection; five patients recovered without sequelae and one patient died because of late complications. We propose that in patients with chronic liver disease and active pneumonia transplantation is a treatment option that should not hastily be abandoned.
AB - Patients with chronic liver disease are at high risk for severe infection because of increased bacterial translocation and immune suppression associated with liver dysfunction. Patients presenting with severe pneumonia and acute decompensation of cirrhosis are generally not considered for liver transplantation because it is unknown if these patients can recover from infection while under immunosuppression. We performed an observational study where patients with cirrhosis of the liver remained on the waiting list, although suffering from active pneumonia. Nine patients were included, but only six patients improved under goal-directed therapy and subsequently underwent liver transplantation. All six patients recovered quickly from infection; five patients recovered without sequelae and one patient died because of late complications. We propose that in patients with chronic liver disease and active pneumonia transplantation is a treatment option that should not hastily be abandoned.
KW - Humans
KW - Male
KW - Female
KW - Middle Aged
KW - Treatment Outcome
KW - Waiting Lists
KW - Liver Transplantation
KW - Liver Cirrhosis/surgery
KW - Pneumonia/surgery
KW - Humans
KW - Male
KW - Female
KW - Middle Aged
KW - Treatment Outcome
KW - Waiting Lists
KW - Liver Transplantation
KW - Liver Cirrhosis/surgery
KW - Pneumonia/surgery
M3 - SCORING: Journal article
VL - 24
SP - 1068
EP - 1074
JO - TRANSPL INT
JF - TRANSPL INT
SN - 0934-0874
IS - 11
M1 - 11
ER -