Laser Flare Photometry in Primary Rhegmatogenous Retinal Detachment

TY - JOUR

T1 - Laser Flare Photometry in Primary Rhegmatogenous Retinal Detachment

T2 - an Evaluation of 2487 Cases

AU - Gietzelt, Caroline

AU - Hoerster, Robert

AU - Schiller, Petra

AU - Hermann, Saskia

AU - Kraus, Daria

AU - Holz, Frank G

AU - Guthoff, Rainer

AU - Agostini, Hansjürgen

AU - Spitzer, Martin S

AU - Wiedemann, Peter

AU - Lommatzsch, Albrecht

AU - Boden, Karl T

AU - Bartz-Schmidt, Ulrich

AU - Bemme, Sebastian

AU - Tamm, Svenja

AU - Maier, Mathias

AU - Roider, Johann

AU - Kirchhof, Bernd

AU - Fauser, Sascha

AU - Schaub, Friederike

AU - PRIVENT Study Group

PY - 2024/5/1

Y1 - 2024/5/1

N2 - PURPOSE: Exploratory analysis associated with the prospective, multicenter, randomized PRIVENT trial. To characterize the associations between laser flare photometry and anatomical and epidemiological features of rhegmatogenous retinal detachment (RRD).METHODS: The authors measured laser flare values of all 3,048 prescreened patients excluding those with comorbidities. A mixed regression analysis evaluated the strength of the influencing factors like age, sex, lens status, and presence and extent of RRD on laser flare.RESULTS: Rhegmatogenous retinal detachment was more frequent in men (65.8%) than in women (34.2%, P < 0.001) and in right (52%) than in left eyes (48%, P = 0.045). Phakic RRD affected less quadrants and was less likely to be associated with macula-off status than pseudophakic RRD (48.4% vs. 58.0% macula off, 23% vs. 31% ≥3 quadrants, P < 0.001). Laser flare of affected eyes was significantly higher compared with fellow eyes (12.6 ± 15.2 vs. 8.3 ± 7.4 pc/ms, P < 0.001). The factors age, sex, lens status, presence of RRD, and the number of quadrants affected were independent influencing factors on laser flare. R 2 was 0.145 for phakic and 0.094 for pseudophakic eyes.CONCLUSION: The results indicate that there may be more factors affecting laser flare than previously assumed. This might limit flare as predictive value for PVR and retinal redetachment.

AB - PURPOSE: Exploratory analysis associated with the prospective, multicenter, randomized PRIVENT trial. To characterize the associations between laser flare photometry and anatomical and epidemiological features of rhegmatogenous retinal detachment (RRD).METHODS: The authors measured laser flare values of all 3,048 prescreened patients excluding those with comorbidities. A mixed regression analysis evaluated the strength of the influencing factors like age, sex, lens status, and presence and extent of RRD on laser flare.RESULTS: Rhegmatogenous retinal detachment was more frequent in men (65.8%) than in women (34.2%, P < 0.001) and in right (52%) than in left eyes (48%, P = 0.045). Phakic RRD affected less quadrants and was less likely to be associated with macula-off status than pseudophakic RRD (48.4% vs. 58.0% macula off, 23% vs. 31% ≥3 quadrants, P < 0.001). Laser flare of affected eyes was significantly higher compared with fellow eyes (12.6 ± 15.2 vs. 8.3 ± 7.4 pc/ms, P < 0.001). The factors age, sex, lens status, presence of RRD, and the number of quadrants affected were independent influencing factors on laser flare. R 2 was 0.145 for phakic and 0.094 for pseudophakic eyes.CONCLUSION: The results indicate that there may be more factors affecting laser flare than previously assumed. This might limit flare as predictive value for PVR and retinal redetachment.

KW - Adult

KW - Aged

KW - Female

KW - Humans

KW - Lasers

KW - Male

KW - Middle Aged

KW - Photometry/methods

KW - Prospective Studies

KW - Retinal Detachment/diagnosis

KW - Visual Acuity/physiology

U2 - 10.1097/IAE.0000000000004026

DO - 10.1097/IAE.0000000000004026

M3 - SCORING: Journal article

C2 - 38181515

VL - 44

SP - 764

EP - 773

JO - RETINA-J RET VIT DIS

JF - RETINA-J RET VIT DIS

SN - 0275-004X

IS - 5

ER -