Laser Flare Photometry in Primary Rhegmatogenous Retinal Detachment
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Laser Flare Photometry in Primary Rhegmatogenous Retinal Detachment : an Evaluation of 2487 Cases. / Gietzelt, Caroline; Hoerster, Robert; Schiller, Petra; Hermann, Saskia; Kraus, Daria; Holz, Frank G; Guthoff, Rainer; Agostini, Hansjürgen; Spitzer, Martin S; Wiedemann, Peter; Lommatzsch, Albrecht; Boden, Karl T; Bartz-Schmidt, Ulrich; Bemme, Sebastian; Tamm, Svenja; Maier, Mathias; Roider, Johann; Kirchhof, Bernd; Fauser, Sascha; Schaub, Friederike; PRIVENT Study Group.
in: RETINA-J RET VIT DIS, Jahrgang 44, Nr. 5, 01.05.2024, S. 764-773.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Laser Flare Photometry in Primary Rhegmatogenous Retinal Detachment
T2 - an Evaluation of 2487 Cases
AU - Gietzelt, Caroline
AU - Hoerster, Robert
AU - Schiller, Petra
AU - Hermann, Saskia
AU - Kraus, Daria
AU - Holz, Frank G
AU - Guthoff, Rainer
AU - Agostini, Hansjürgen
AU - Spitzer, Martin S
AU - Wiedemann, Peter
AU - Lommatzsch, Albrecht
AU - Boden, Karl T
AU - Bartz-Schmidt, Ulrich
AU - Bemme, Sebastian
AU - Tamm, Svenja
AU - Maier, Mathias
AU - Roider, Johann
AU - Kirchhof, Bernd
AU - Fauser, Sascha
AU - Schaub, Friederike
AU - PRIVENT Study Group
PY - 2024/5/1
Y1 - 2024/5/1
N2 - PURPOSE: Exploratory analysis associated with the prospective, multicenter, randomized PRIVENT trial. To characterize the associations between laser flare photometry and anatomical and epidemiological features of rhegmatogenous retinal detachment (RRD).METHODS: The authors measured laser flare values of all 3,048 prescreened patients excluding those with comorbidities. A mixed regression analysis evaluated the strength of the influencing factors like age, sex, lens status, and presence and extent of RRD on laser flare.RESULTS: Rhegmatogenous retinal detachment was more frequent in men (65.8%) than in women (34.2%, P < 0.001) and in right (52%) than in left eyes (48%, P = 0.045). Phakic RRD affected less quadrants and was less likely to be associated with macula-off status than pseudophakic RRD (48.4% vs. 58.0% macula off, 23% vs. 31% ≥3 quadrants, P < 0.001). Laser flare of affected eyes was significantly higher compared with fellow eyes (12.6 ± 15.2 vs. 8.3 ± 7.4 pc/ms, P < 0.001). The factors age, sex, lens status, presence of RRD, and the number of quadrants affected were independent influencing factors on laser flare. R 2 was 0.145 for phakic and 0.094 for pseudophakic eyes.CONCLUSION: The results indicate that there may be more factors affecting laser flare than previously assumed. This might limit flare as predictive value for PVR and retinal redetachment.
AB - PURPOSE: Exploratory analysis associated with the prospective, multicenter, randomized PRIVENT trial. To characterize the associations between laser flare photometry and anatomical and epidemiological features of rhegmatogenous retinal detachment (RRD).METHODS: The authors measured laser flare values of all 3,048 prescreened patients excluding those with comorbidities. A mixed regression analysis evaluated the strength of the influencing factors like age, sex, lens status, and presence and extent of RRD on laser flare.RESULTS: Rhegmatogenous retinal detachment was more frequent in men (65.8%) than in women (34.2%, P < 0.001) and in right (52%) than in left eyes (48%, P = 0.045). Phakic RRD affected less quadrants and was less likely to be associated with macula-off status than pseudophakic RRD (48.4% vs. 58.0% macula off, 23% vs. 31% ≥3 quadrants, P < 0.001). Laser flare of affected eyes was significantly higher compared with fellow eyes (12.6 ± 15.2 vs. 8.3 ± 7.4 pc/ms, P < 0.001). The factors age, sex, lens status, presence of RRD, and the number of quadrants affected were independent influencing factors on laser flare. R 2 was 0.145 for phakic and 0.094 for pseudophakic eyes.CONCLUSION: The results indicate that there may be more factors affecting laser flare than previously assumed. This might limit flare as predictive value for PVR and retinal redetachment.
KW - Adult
KW - Aged
KW - Female
KW - Humans
KW - Lasers
KW - Male
KW - Middle Aged
KW - Photometry/methods
KW - Prospective Studies
KW - Retinal Detachment/diagnosis
KW - Visual Acuity/physiology
U2 - 10.1097/IAE.0000000000004026
DO - 10.1097/IAE.0000000000004026
M3 - SCORING: Journal article
C2 - 38181515
VL - 44
SP - 764
EP - 773
JO - RETINA-J RET VIT DIS
JF - RETINA-J RET VIT DIS
SN - 0275-004X
IS - 5
ER -