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Intravital Imaging of Thrombosis Models in Mice

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Intravital Imaging of Thrombosis Models in Mice. / Kiouptsi, Klytaimnistra; Casari, Martina; Mandel, Jonathan; Gao, Zhenling; Deppermann, Carsten.

In: HAMOSTASEOLOGIE, Vol. 43, No. 5, 10.2023, p. 348-359.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Kiouptsi, K, Casari, M, Mandel, J, Gao, Z & Deppermann, C 2023, 'Intravital Imaging of Thrombosis Models in Mice', HAMOSTASEOLOGIE, vol. 43, no. 5, pp. 348-359. https://doi.org/10.1055/a-2118-2932

APA

Kiouptsi, K., Casari, M., Mandel, J., Gao, Z., & Deppermann, C. (2023). Intravital Imaging of Thrombosis Models in Mice. HAMOSTASEOLOGIE, 43(5), 348-359. https://doi.org/10.1055/a-2118-2932

Vancouver

Kiouptsi K, Casari M, Mandel J, Gao Z, Deppermann C. Intravital Imaging of Thrombosis Models in Mice. HAMOSTASEOLOGIE. 2023 Oct;43(5):348-359. https://doi.org/10.1055/a-2118-2932

Bibtex

@article{b3d84b2a38394085bef8ab9e2887ad19,
title = "Intravital Imaging of Thrombosis Models in Mice",
abstract = "Intravital microscopy is a powerful tool to study thrombosis in real time. The kinetics of thrombus formation and progression in vivo is studied after inflicting damage to the endothelium through mechanical, chemical, or laser injury. Mouse models of atherosclerosis are also used to induce thrombus formation. Vessels of different sizes and from different vascular beds such as carotid artery or vena cava, mesenteric or cremaster arterioles, can be targeted. Using fluorescent dyes, antibodies, or reporter mouse strains allows to visualize key cells and factors mediating the thrombotic processes. Here, we review the latest literature on using intravital microscopy to study thrombosis as well as thromboinflammation following transient middle cerebral artery occlusion, infection-induced immunothrombosis, and liver ischemia reperfusion.",
keywords = "Animals, Mice, Thrombosis, Inflammation, Disease Models, Animal, Intravital Microscopy, Endothelium",
author = "Klytaimnistra Kiouptsi and Martina Casari and Jonathan Mandel and Zhenling Gao and Carsten Deppermann",
note = "Thieme. All rights reserved.",
year = "2023",
month = oct,
doi = "10.1055/a-2118-2932",
language = "English",
volume = "43",
pages = "348--359",
journal = "HAMOSTASEOLOGIE",
issn = "0720-9355",
publisher = "Schattauer",
number = "5",

}

RIS

TY - JOUR

T1 - Intravital Imaging of Thrombosis Models in Mice

AU - Kiouptsi, Klytaimnistra

AU - Casari, Martina

AU - Mandel, Jonathan

AU - Gao, Zhenling

AU - Deppermann, Carsten

N1 - Thieme. All rights reserved.

PY - 2023/10

Y1 - 2023/10

N2 - Intravital microscopy is a powerful tool to study thrombosis in real time. The kinetics of thrombus formation and progression in vivo is studied after inflicting damage to the endothelium through mechanical, chemical, or laser injury. Mouse models of atherosclerosis are also used to induce thrombus formation. Vessels of different sizes and from different vascular beds such as carotid artery or vena cava, mesenteric or cremaster arterioles, can be targeted. Using fluorescent dyes, antibodies, or reporter mouse strains allows to visualize key cells and factors mediating the thrombotic processes. Here, we review the latest literature on using intravital microscopy to study thrombosis as well as thromboinflammation following transient middle cerebral artery occlusion, infection-induced immunothrombosis, and liver ischemia reperfusion.

AB - Intravital microscopy is a powerful tool to study thrombosis in real time. The kinetics of thrombus formation and progression in vivo is studied after inflicting damage to the endothelium through mechanical, chemical, or laser injury. Mouse models of atherosclerosis are also used to induce thrombus formation. Vessels of different sizes and from different vascular beds such as carotid artery or vena cava, mesenteric or cremaster arterioles, can be targeted. Using fluorescent dyes, antibodies, or reporter mouse strains allows to visualize key cells and factors mediating the thrombotic processes. Here, we review the latest literature on using intravital microscopy to study thrombosis as well as thromboinflammation following transient middle cerebral artery occlusion, infection-induced immunothrombosis, and liver ischemia reperfusion.

KW - Animals

KW - Mice

KW - Thrombosis

KW - Inflammation

KW - Disease Models, Animal

KW - Intravital Microscopy

KW - Endothelium

U2 - 10.1055/a-2118-2932

DO - 10.1055/a-2118-2932

M3 - SCORING: Review article

C2 - 37857297

VL - 43

SP - 348

EP - 359

JO - HAMOSTASEOLOGIE

JF - HAMOSTASEOLOGIE

SN - 0720-9355

IS - 5

ER -