Intraoperative application of "white test" to reduce postoperative bile leak after major liver resection
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Intraoperative application of "white test" to reduce postoperative bile leak after major liver resection : results of a prospective cohort study in 137 patients. / Li, Jun; Malagó, Massimo; Sotiropoulos, Georgios C; Lang, Hauke; Schaffer, Randolph; Paul, Andreas; Broelsch, Christoph E; Nadalin, Silvio.
In: LANGENBECK ARCH SURG, Vol. 394, No. 6, 11.2009, p. 1019-24.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Intraoperative application of "white test" to reduce postoperative bile leak after major liver resection
T2 - results of a prospective cohort study in 137 patients
AU - Li, Jun
AU - Malagó, Massimo
AU - Sotiropoulos, Georgios C
AU - Lang, Hauke
AU - Schaffer, Randolph
AU - Paul, Andreas
AU - Broelsch, Christoph E
AU - Nadalin, Silvio
PY - 2009/11
Y1 - 2009/11
N2 - PURPOSE: This study aimed to prove the clinical validation of the recently developed bile leakage test, "white test" (WT), in major liver resection.MATERIALS AND METHODS: From June 2005 to June 2007, the study was carried out in a prospective consecutive fashion, including 74 patients without bile leakage test as the control group while 63 patients undergoing white test as the study group. The incidences of bile leakage within the 30th postoperative day in both groups were compared.RESULTS: Postoperative bile leakage was found in 22.9% patients in the control group and in 5.3% patients in the WT group, respectively (p < 0.01). In univariate analysis, not performing a white test, Klatskin tumor, biliary-enteric anastomosis, and longer operation time were associated with an increase of bile leakage. The multivariate analysis showed that not performing the WT was the only significant factor influencing the occurrence of postoperative bile leakage (p = 0.02).CONCLUSIONS: The white test is a feasible and sensitive bile leakage test with no obvious disadvantages. It could be a possible standardized method to prevent bile leakage in major liver resection.
AB - PURPOSE: This study aimed to prove the clinical validation of the recently developed bile leakage test, "white test" (WT), in major liver resection.MATERIALS AND METHODS: From June 2005 to June 2007, the study was carried out in a prospective consecutive fashion, including 74 patients without bile leakage test as the control group while 63 patients undergoing white test as the study group. The incidences of bile leakage within the 30th postoperative day in both groups were compared.RESULTS: Postoperative bile leakage was found in 22.9% patients in the control group and in 5.3% patients in the WT group, respectively (p < 0.01). In univariate analysis, not performing a white test, Klatskin tumor, biliary-enteric anastomosis, and longer operation time were associated with an increase of bile leakage. The multivariate analysis showed that not performing the WT was the only significant factor influencing the occurrence of postoperative bile leakage (p = 0.02).CONCLUSIONS: The white test is a feasible and sensitive bile leakage test with no obvious disadvantages. It could be a possible standardized method to prevent bile leakage in major liver resection.
KW - Adolescent
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Bile
KW - Cohort Studies
KW - Fat Emulsions, Intravenous
KW - Feasibility Studies
KW - Hepatectomy
KW - Humans
KW - Incidence
KW - Intraoperative Care
KW - Liver Neoplasms
KW - Middle Aged
KW - Postoperative Complications
KW - Predictive Value of Tests
KW - Young Adult
KW - Controlled Clinical Trial
KW - Journal Article
U2 - 10.1007/s00423-008-0455-7
DO - 10.1007/s00423-008-0455-7
M3 - SCORING: Journal article
C2 - 19104825
VL - 394
SP - 1019
EP - 1024
JO - LANGENBECK ARCH SURG
JF - LANGENBECK ARCH SURG
SN - 1435-2443
IS - 6
ER -