Intraoperative application of "white test" to reduce postoperative bile leak after major liver resection

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Intraoperative application of "white test" to reduce postoperative bile leak after major liver resection : results of a prospective cohort study in 137 patients. / Li, Jun; Malagó, Massimo; Sotiropoulos, Georgios C; Lang, Hauke; Schaffer, Randolph; Paul, Andreas; Broelsch, Christoph E; Nadalin, Silvio.

in: LANGENBECK ARCH SURG, Jahrgang 394, Nr. 6, 11.2009, S. 1019-24.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{6d8c1b2651944200b44bb42b8593d2eb,
title = "Intraoperative application of {"}white test{"} to reduce postoperative bile leak after major liver resection: results of a prospective cohort study in 137 patients",
abstract = "PURPOSE: This study aimed to prove the clinical validation of the recently developed bile leakage test, {"}white test{"} (WT), in major liver resection.MATERIALS AND METHODS: From June 2005 to June 2007, the study was carried out in a prospective consecutive fashion, including 74 patients without bile leakage test as the control group while 63 patients undergoing white test as the study group. The incidences of bile leakage within the 30th postoperative day in both groups were compared.RESULTS: Postoperative bile leakage was found in 22.9% patients in the control group and in 5.3% patients in the WT group, respectively (p < 0.01). In univariate analysis, not performing a white test, Klatskin tumor, biliary-enteric anastomosis, and longer operation time were associated with an increase of bile leakage. The multivariate analysis showed that not performing the WT was the only significant factor influencing the occurrence of postoperative bile leakage (p = 0.02).CONCLUSIONS: The white test is a feasible and sensitive bile leakage test with no obvious disadvantages. It could be a possible standardized method to prevent bile leakage in major liver resection.",
keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Bile, Cohort Studies, Fat Emulsions, Intravenous, Feasibility Studies, Hepatectomy, Humans, Incidence, Intraoperative Care, Liver Neoplasms, Middle Aged, Postoperative Complications, Predictive Value of Tests, Young Adult, Controlled Clinical Trial, Journal Article",
author = "Jun Li and Massimo Malag{\'o} and Sotiropoulos, {Georgios C} and Hauke Lang and Randolph Schaffer and Andreas Paul and Broelsch, {Christoph E} and Silvio Nadalin",
year = "2009",
month = nov,
doi = "10.1007/s00423-008-0455-7",
language = "English",
volume = "394",
pages = "1019--24",
journal = "LANGENBECK ARCH SURG",
issn = "1435-2443",
publisher = "Springer",
number = "6",

}

RIS

TY - JOUR

T1 - Intraoperative application of "white test" to reduce postoperative bile leak after major liver resection

T2 - results of a prospective cohort study in 137 patients

AU - Li, Jun

AU - Malagó, Massimo

AU - Sotiropoulos, Georgios C

AU - Lang, Hauke

AU - Schaffer, Randolph

AU - Paul, Andreas

AU - Broelsch, Christoph E

AU - Nadalin, Silvio

PY - 2009/11

Y1 - 2009/11

N2 - PURPOSE: This study aimed to prove the clinical validation of the recently developed bile leakage test, "white test" (WT), in major liver resection.MATERIALS AND METHODS: From June 2005 to June 2007, the study was carried out in a prospective consecutive fashion, including 74 patients without bile leakage test as the control group while 63 patients undergoing white test as the study group. The incidences of bile leakage within the 30th postoperative day in both groups were compared.RESULTS: Postoperative bile leakage was found in 22.9% patients in the control group and in 5.3% patients in the WT group, respectively (p < 0.01). In univariate analysis, not performing a white test, Klatskin tumor, biliary-enteric anastomosis, and longer operation time were associated with an increase of bile leakage. The multivariate analysis showed that not performing the WT was the only significant factor influencing the occurrence of postoperative bile leakage (p = 0.02).CONCLUSIONS: The white test is a feasible and sensitive bile leakage test with no obvious disadvantages. It could be a possible standardized method to prevent bile leakage in major liver resection.

AB - PURPOSE: This study aimed to prove the clinical validation of the recently developed bile leakage test, "white test" (WT), in major liver resection.MATERIALS AND METHODS: From June 2005 to June 2007, the study was carried out in a prospective consecutive fashion, including 74 patients without bile leakage test as the control group while 63 patients undergoing white test as the study group. The incidences of bile leakage within the 30th postoperative day in both groups were compared.RESULTS: Postoperative bile leakage was found in 22.9% patients in the control group and in 5.3% patients in the WT group, respectively (p < 0.01). In univariate analysis, not performing a white test, Klatskin tumor, biliary-enteric anastomosis, and longer operation time were associated with an increase of bile leakage. The multivariate analysis showed that not performing the WT was the only significant factor influencing the occurrence of postoperative bile leakage (p = 0.02).CONCLUSIONS: The white test is a feasible and sensitive bile leakage test with no obvious disadvantages. It could be a possible standardized method to prevent bile leakage in major liver resection.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Bile

KW - Cohort Studies

KW - Fat Emulsions, Intravenous

KW - Feasibility Studies

KW - Hepatectomy

KW - Humans

KW - Incidence

KW - Intraoperative Care

KW - Liver Neoplasms

KW - Middle Aged

KW - Postoperative Complications

KW - Predictive Value of Tests

KW - Young Adult

KW - Controlled Clinical Trial

KW - Journal Article

U2 - 10.1007/s00423-008-0455-7

DO - 10.1007/s00423-008-0455-7

M3 - SCORING: Journal article

C2 - 19104825

VL - 394

SP - 1019

EP - 1024

JO - LANGENBECK ARCH SURG

JF - LANGENBECK ARCH SURG

SN - 1435-2443

IS - 6

ER -