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Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality

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Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality. / Milovanovic, Petar; Busse, Björn.

In: CURR OSTEOPOROS REP, Vol. 17, No. 3, 06.2019, p. 105-115.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Milovanovic, P & Busse, B 2019, 'Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality', CURR OSTEOPOROS REP, vol. 17, no. 3, pp. 105-115. https://doi.org/10.1007/s11914-019-00508-y

APA

Milovanovic, P., & Busse, B. (2019). Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality. CURR OSTEOPOROS REP, 17(3), 105-115. https://doi.org/10.1007/s11914-019-00508-y

Vancouver

Milovanovic P, Busse B. Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality. CURR OSTEOPOROS REP. 2019 Jun;17(3):105-115. https://doi.org/10.1007/s11914-019-00508-y

Bibtex

@article{096b6f56635044a2a89e3d7b5e467be4,
title = "Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality",
abstract = "PURPOSE OF REVIEW: This article provides a review on the variability of the osteocyte lacunar network in the human skeleton. It highlights characteristics of the osteocyte lacunar network in relation to different skeletal sites and fracture susceptibility.RECENT FINDINGS: Application of 2D analyses (quantitative backscattered electron microscopy, histology, confocal laser scanning microscopy) and 3D reconstructions (microcomputed tomography and synchrotron radiation microcomputed tomography) provides extended high-resolution information on osteocyte lacunar properties in individuals of various age (fetal, children's growth, elderly), sex, and disease states with increased fracture risk. Recent findings on the distribution of osteocytes in the human skeleton are reviewed. Quantitative data highlighting the variability of the osteocyte lacunar network is presented with special emphasis on site specificity and maintenance of bone health. The causes and consequences of heterogeneous distribution of osteocyte lacunae both within specific regions of interest and on the skeletal level are reviewed and linked to differential bone quality factors and fracture susceptibility.",
author = "Petar Milovanovic and Bj{\"o}rn Busse",
year = "2019",
month = jun,
doi = "10.1007/s11914-019-00508-y",
language = "English",
volume = "17",
pages = "105--115",
journal = "CURR OSTEOPOROS REP",
issn = "1544-1873",
publisher = "SPRINGER US",
number = "3",

}

RIS

TY - JOUR

T1 - Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality

AU - Milovanovic, Petar

AU - Busse, Björn

PY - 2019/6

Y1 - 2019/6

N2 - PURPOSE OF REVIEW: This article provides a review on the variability of the osteocyte lacunar network in the human skeleton. It highlights characteristics of the osteocyte lacunar network in relation to different skeletal sites and fracture susceptibility.RECENT FINDINGS: Application of 2D analyses (quantitative backscattered electron microscopy, histology, confocal laser scanning microscopy) and 3D reconstructions (microcomputed tomography and synchrotron radiation microcomputed tomography) provides extended high-resolution information on osteocyte lacunar properties in individuals of various age (fetal, children's growth, elderly), sex, and disease states with increased fracture risk. Recent findings on the distribution of osteocytes in the human skeleton are reviewed. Quantitative data highlighting the variability of the osteocyte lacunar network is presented with special emphasis on site specificity and maintenance of bone health. The causes and consequences of heterogeneous distribution of osteocyte lacunae both within specific regions of interest and on the skeletal level are reviewed and linked to differential bone quality factors and fracture susceptibility.

AB - PURPOSE OF REVIEW: This article provides a review on the variability of the osteocyte lacunar network in the human skeleton. It highlights characteristics of the osteocyte lacunar network in relation to different skeletal sites and fracture susceptibility.RECENT FINDINGS: Application of 2D analyses (quantitative backscattered electron microscopy, histology, confocal laser scanning microscopy) and 3D reconstructions (microcomputed tomography and synchrotron radiation microcomputed tomography) provides extended high-resolution information on osteocyte lacunar properties in individuals of various age (fetal, children's growth, elderly), sex, and disease states with increased fracture risk. Recent findings on the distribution of osteocytes in the human skeleton are reviewed. Quantitative data highlighting the variability of the osteocyte lacunar network is presented with special emphasis on site specificity and maintenance of bone health. The causes and consequences of heterogeneous distribution of osteocyte lacunae both within specific regions of interest and on the skeletal level are reviewed and linked to differential bone quality factors and fracture susceptibility.

U2 - 10.1007/s11914-019-00508-y

DO - 10.1007/s11914-019-00508-y

M3 - SCORING: Review article

C2 - 30980284

VL - 17

SP - 105

EP - 115

JO - CURR OSTEOPOROS REP

JF - CURR OSTEOPOROS REP

SN - 1544-1873

IS - 3

ER -