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Initial results after implementation of a multimodal treatment for peritoneal malignancies

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Initial results after implementation of a multimodal treatment for peritoneal malignancies. / Raue, W; Tsilimparis, N; Langelotz, C; Rau, B; Schwenk, W; Hartmann, J.

In: ACTA CHIR BELG, Vol. 111, No. 2, 31.05.2011, p. 68-72.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Raue, W, Tsilimparis, N, Langelotz, C, Rau, B, Schwenk, W & Hartmann, J 2011, 'Initial results after implementation of a multimodal treatment for peritoneal malignancies', ACTA CHIR BELG, vol. 111, no. 2, pp. 68-72. https://doi.org/10.1080/00015458.2011.11680709

APA

Raue, W., Tsilimparis, N., Langelotz, C., Rau, B., Schwenk, W., & Hartmann, J. (2011). Initial results after implementation of a multimodal treatment for peritoneal malignancies. ACTA CHIR BELG, 111(2), 68-72. https://doi.org/10.1080/00015458.2011.11680709

Vancouver

Raue W, Tsilimparis N, Langelotz C, Rau B, Schwenk W, Hartmann J. Initial results after implementation of a multimodal treatment for peritoneal malignancies. ACTA CHIR BELG. 2011 May 31;111(2):68-72. https://doi.org/10.1080/00015458.2011.11680709

Bibtex

@article{6d8817787cff49ae8383e851a92c7862,
title = "Initial results after implementation of a multimodal treatment for peritoneal malignancies",
abstract = "INTRODUCTION: Peritoneal carcinomatosis represents a clinical condition with a limited perspective concerning long term survival. The combination of surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) represents a complex multimodal therapeutic management concept with promising results for prolongation of survival. For the identification of pitfalls during implementation of the HIPEC procedure into clinical practice an observational study was conducted.METHODS: Between 2005 and 2009 data from all patients treated with cytoreductive surgery and HIPEC for peritoneal carcinomatosis was prospectively collected and analysed.RESULTS: During the observational interval a total of 42 patients underwent surgical treatment for peritoneal carcinomatosis. In 34 patients the complete procedure with surgical cytoreduction and HIPEC was performed. Perioperative mortality (6%) and morbidity (35%) was similar to other reported series. Twenty-five patients (76%) survived the 18 months follow-up period after complete procedure.CONCLUSION: The multimodal therapeutic treatment concept of surgical cytoreduction and following HIPEC leads to promising results for patients suffering from peritoneal carcinomatosis. However this treatment concept is afflicted with a relevant risk of postoperative complications.",
keywords = "Adult, Aged, Anastomosis, Surgical, Antineoplastic Combined Chemotherapy Protocols/administration & dosage, Combined Modality Therapy, Female, Humans, Hyperthermia, Induced, Injections, Intraperitoneal, Male, Middle Aged, Ovarian Neoplasms/pathology, Peritoneal Neoplasms/mortality, Peritoneum/surgery, Postoperative Complications/epidemiology, Pseudomyxoma Peritonei/therapy",
author = "W Raue and N Tsilimparis and C Langelotz and B Rau and W Schwenk and J Hartmann",
year = "2011",
month = may,
day = "31",
doi = "10.1080/00015458.2011.11680709",
language = "English",
volume = "111",
pages = "68--72",
journal = "ACTA CHIR BELG",
issn = "0001-5458",
publisher = "ARSMB-KVBMG",
number = "2",

}

RIS

TY - JOUR

T1 - Initial results after implementation of a multimodal treatment for peritoneal malignancies

AU - Raue, W

AU - Tsilimparis, N

AU - Langelotz, C

AU - Rau, B

AU - Schwenk, W

AU - Hartmann, J

PY - 2011/5/31

Y1 - 2011/5/31

N2 - INTRODUCTION: Peritoneal carcinomatosis represents a clinical condition with a limited perspective concerning long term survival. The combination of surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) represents a complex multimodal therapeutic management concept with promising results for prolongation of survival. For the identification of pitfalls during implementation of the HIPEC procedure into clinical practice an observational study was conducted.METHODS: Between 2005 and 2009 data from all patients treated with cytoreductive surgery and HIPEC for peritoneal carcinomatosis was prospectively collected and analysed.RESULTS: During the observational interval a total of 42 patients underwent surgical treatment for peritoneal carcinomatosis. In 34 patients the complete procedure with surgical cytoreduction and HIPEC was performed. Perioperative mortality (6%) and morbidity (35%) was similar to other reported series. Twenty-five patients (76%) survived the 18 months follow-up period after complete procedure.CONCLUSION: The multimodal therapeutic treatment concept of surgical cytoreduction and following HIPEC leads to promising results for patients suffering from peritoneal carcinomatosis. However this treatment concept is afflicted with a relevant risk of postoperative complications.

AB - INTRODUCTION: Peritoneal carcinomatosis represents a clinical condition with a limited perspective concerning long term survival. The combination of surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) represents a complex multimodal therapeutic management concept with promising results for prolongation of survival. For the identification of pitfalls during implementation of the HIPEC procedure into clinical practice an observational study was conducted.METHODS: Between 2005 and 2009 data from all patients treated with cytoreductive surgery and HIPEC for peritoneal carcinomatosis was prospectively collected and analysed.RESULTS: During the observational interval a total of 42 patients underwent surgical treatment for peritoneal carcinomatosis. In 34 patients the complete procedure with surgical cytoreduction and HIPEC was performed. Perioperative mortality (6%) and morbidity (35%) was similar to other reported series. Twenty-five patients (76%) survived the 18 months follow-up period after complete procedure.CONCLUSION: The multimodal therapeutic treatment concept of surgical cytoreduction and following HIPEC leads to promising results for patients suffering from peritoneal carcinomatosis. However this treatment concept is afflicted with a relevant risk of postoperative complications.

KW - Adult

KW - Aged

KW - Anastomosis, Surgical

KW - Antineoplastic Combined Chemotherapy Protocols/administration & dosage

KW - Combined Modality Therapy

KW - Female

KW - Humans

KW - Hyperthermia, Induced

KW - Injections, Intraperitoneal

KW - Male

KW - Middle Aged

KW - Ovarian Neoplasms/pathology

KW - Peritoneal Neoplasms/mortality

KW - Peritoneum/surgery

KW - Postoperative Complications/epidemiology

KW - Pseudomyxoma Peritonei/therapy

U2 - 10.1080/00015458.2011.11680709

DO - 10.1080/00015458.2011.11680709

M3 - SCORING: Journal article

C2 - 21618850

VL - 111

SP - 68

EP - 72

JO - ACTA CHIR BELG

JF - ACTA CHIR BELG

SN - 0001-5458

IS - 2

ER -