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Increased sensory feedback in Tourette syndrome.

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Increased sensory feedback in Tourette syndrome. / Biermann-Ruben, Katja; Miller, Anastasia; Franzkowiak, Stephanie; Finis, Jennifer; Pollok, Bettina; Wach, Claudia; Südmeyer, Martin; Jonas, Melanie; Thomalla, Götz; Müller-Vahl, Kirsten; Münchau, Alexander; Schnitzler, Alfons.

In: NEUROIMAGE, Vol. 63, No. 1, 1, 2012, p. 119-125.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Biermann-Ruben, K, Miller, A, Franzkowiak, S, Finis, J, Pollok, B, Wach, C, Südmeyer, M, Jonas, M, Thomalla, G, Müller-Vahl, K, Münchau, A & Schnitzler, A 2012, 'Increased sensory feedback in Tourette syndrome.', NEUROIMAGE, vol. 63, no. 1, 1, pp. 119-125. <http://www.ncbi.nlm.nih.gov/pubmed/22776453?dopt=Citation>

APA

Biermann-Ruben, K., Miller, A., Franzkowiak, S., Finis, J., Pollok, B., Wach, C., Südmeyer, M., Jonas, M., Thomalla, G., Müller-Vahl, K., Münchau, A., & Schnitzler, A. (2012). Increased sensory feedback in Tourette syndrome. NEUROIMAGE, 63(1), 119-125. [1]. http://www.ncbi.nlm.nih.gov/pubmed/22776453?dopt=Citation

Vancouver

Biermann-Ruben K, Miller A, Franzkowiak S, Finis J, Pollok B, Wach C et al. Increased sensory feedback in Tourette syndrome. NEUROIMAGE. 2012;63(1):119-125. 1.

Bibtex

@article{6713fa9cb8e24512862fc4f180942fe2,
title = "Increased sensory feedback in Tourette syndrome.",
abstract = "Tourette syndrome (TS) is a neuro-psychiatric disorder being characterized by motor and phonic tics typically preceded by sensory urges. Given the latter the role of the sensory system and sensorimotor interaction in TS has recently gained increased attention. 12 TS patients and 12 matched control subjects performed two tasks, requiring simple finger movements: a Go/NoGo task and a self paced movement task. Neurophysiological data was recorded using magnetoencephalography (MEG). Event related responses around movement onset, i.e. motor field (MF) occurring directly prior to the movement and movement evoked field (MEF) immediately after movement onset were analyzed using dipole modeling. MF peak amplitudes did not differ between groups in either task. In contrast, in both tasks MEF peak amplitudes were increased in TS patients. Moreover, larger MEF amplitudes during self paced movements were inversely correlated with motor tic frequency and severity. Enlarged MEF amplitudes as a marker of early sensory feedback of one's own movements probably represent enlarged sensory input from the periphery resulting from altered subcortical gating. We conclude that TS patients exhibit altered sensory-motor processing involved in voluntary movement control, which might also be successful in tic control.",
keywords = "Adult, Humans, Male, Female, Middle Aged, Young Adult, Brain Mapping, Magnetoencephalography, Tourette Syndrome/*physiopathology, *Evoked Potentials, Motor, *Movement, Brain/*physiopathology, *Feedback, Sensory, *Volition, Adult, Humans, Male, Female, Middle Aged, Young Adult, Brain Mapping, Magnetoencephalography, Tourette Syndrome/*physiopathology, *Evoked Potentials, Motor, *Movement, Brain/*physiopathology, *Feedback, Sensory, *Volition",
author = "Katja Biermann-Ruben and Anastasia Miller and Stephanie Franzkowiak and Jennifer Finis and Bettina Pollok and Claudia Wach and Martin S{\"u}dmeyer and Melanie Jonas and G{\"o}tz Thomalla and Kirsten M{\"u}ller-Vahl and Alexander M{\"u}nchau and Alfons Schnitzler",
year = "2012",
language = "English",
volume = "63",
pages = "119--125",
journal = "NEUROIMAGE",
issn = "1053-8119",
publisher = "Academic Press",
number = "1",

}

RIS

TY - JOUR

T1 - Increased sensory feedback in Tourette syndrome.

AU - Biermann-Ruben, Katja

AU - Miller, Anastasia

AU - Franzkowiak, Stephanie

AU - Finis, Jennifer

AU - Pollok, Bettina

AU - Wach, Claudia

AU - Südmeyer, Martin

AU - Jonas, Melanie

AU - Thomalla, Götz

AU - Müller-Vahl, Kirsten

AU - Münchau, Alexander

AU - Schnitzler, Alfons

PY - 2012

Y1 - 2012

N2 - Tourette syndrome (TS) is a neuro-psychiatric disorder being characterized by motor and phonic tics typically preceded by sensory urges. Given the latter the role of the sensory system and sensorimotor interaction in TS has recently gained increased attention. 12 TS patients and 12 matched control subjects performed two tasks, requiring simple finger movements: a Go/NoGo task and a self paced movement task. Neurophysiological data was recorded using magnetoencephalography (MEG). Event related responses around movement onset, i.e. motor field (MF) occurring directly prior to the movement and movement evoked field (MEF) immediately after movement onset were analyzed using dipole modeling. MF peak amplitudes did not differ between groups in either task. In contrast, in both tasks MEF peak amplitudes were increased in TS patients. Moreover, larger MEF amplitudes during self paced movements were inversely correlated with motor tic frequency and severity. Enlarged MEF amplitudes as a marker of early sensory feedback of one's own movements probably represent enlarged sensory input from the periphery resulting from altered subcortical gating. We conclude that TS patients exhibit altered sensory-motor processing involved in voluntary movement control, which might also be successful in tic control.

AB - Tourette syndrome (TS) is a neuro-psychiatric disorder being characterized by motor and phonic tics typically preceded by sensory urges. Given the latter the role of the sensory system and sensorimotor interaction in TS has recently gained increased attention. 12 TS patients and 12 matched control subjects performed two tasks, requiring simple finger movements: a Go/NoGo task and a self paced movement task. Neurophysiological data was recorded using magnetoencephalography (MEG). Event related responses around movement onset, i.e. motor field (MF) occurring directly prior to the movement and movement evoked field (MEF) immediately after movement onset were analyzed using dipole modeling. MF peak amplitudes did not differ between groups in either task. In contrast, in both tasks MEF peak amplitudes were increased in TS patients. Moreover, larger MEF amplitudes during self paced movements were inversely correlated with motor tic frequency and severity. Enlarged MEF amplitudes as a marker of early sensory feedback of one's own movements probably represent enlarged sensory input from the periphery resulting from altered subcortical gating. We conclude that TS patients exhibit altered sensory-motor processing involved in voluntary movement control, which might also be successful in tic control.

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Young Adult

KW - Brain Mapping

KW - Magnetoencephalography

KW - Tourette Syndrome/physiopathology

KW - Evoked Potentials, Motor

KW - Movement

KW - Brain/physiopathology

KW - Feedback, Sensory

KW - Volition

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Young Adult

KW - Brain Mapping

KW - Magnetoencephalography

KW - Tourette Syndrome/physiopathology

KW - Evoked Potentials, Motor

KW - Movement

KW - Brain/physiopathology

KW - Feedback, Sensory

KW - Volition

M3 - SCORING: Journal article

VL - 63

SP - 119

EP - 125

JO - NEUROIMAGE

JF - NEUROIMAGE

SN - 1053-8119

IS - 1

M1 - 1

ER -