Importance of Tight Junctions in Relation to Skin Barrier Function

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Importance of Tight Junctions in Relation to Skin Barrier Function. / Brandner, Johanna M.

In: Curr Probl Dermatol, Vol. 49, 2016, p. 27-37.

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@article{51f3e8822b454a3ea883aa322f7ed90a,
title = "Importance of Tight Junctions in Relation to Skin Barrier Function",
abstract = "Tight junctions (TJs) are complex cell-cell junctions that form a barrier in the stratum granulosum of mammalian skin. Besides forming a barrier themselves, TJs influence other skin barriers, e.g. the stratum corneum barrier, and are influenced by other skin barriers, e.g. by the chemical, the microbiome, or the immunological barrier and likely by the basement membrane. This review summarizes the dynamic interaction of the TJ barrier with other barriers in the skin and the central role of TJs in skin barrier function.",
author = "Brandner, {Johanna M}",
note = "{\textcopyright} 2016 S. Karger AG, Basel.",
year = "2016",
doi = "10.1159/000441541",
language = "English",
volume = "49",
pages = "27--37",
journal = "Curr Probl Dermatol",
issn = "1421-5721",
publisher = "KARGER AG",

}

RIS

TY - JOUR

T1 - Importance of Tight Junctions in Relation to Skin Barrier Function

AU - Brandner, Johanna M

N1 - © 2016 S. Karger AG, Basel.

PY - 2016

Y1 - 2016

N2 - Tight junctions (TJs) are complex cell-cell junctions that form a barrier in the stratum granulosum of mammalian skin. Besides forming a barrier themselves, TJs influence other skin barriers, e.g. the stratum corneum barrier, and are influenced by other skin barriers, e.g. by the chemical, the microbiome, or the immunological barrier and likely by the basement membrane. This review summarizes the dynamic interaction of the TJ barrier with other barriers in the skin and the central role of TJs in skin barrier function.

AB - Tight junctions (TJs) are complex cell-cell junctions that form a barrier in the stratum granulosum of mammalian skin. Besides forming a barrier themselves, TJs influence other skin barriers, e.g. the stratum corneum barrier, and are influenced by other skin barriers, e.g. by the chemical, the microbiome, or the immunological barrier and likely by the basement membrane. This review summarizes the dynamic interaction of the TJ barrier with other barriers in the skin and the central role of TJs in skin barrier function.

U2 - 10.1159/000441541

DO - 10.1159/000441541

M3 - SCORING: Journal article

C2 - 26844895

VL - 49

SP - 27

EP - 37

JO - Curr Probl Dermatol

JF - Curr Probl Dermatol

SN - 1421-5721

ER -