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Impact of test environment on the fracture resistance of cortical bone

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Impact of test environment on the fracture resistance of cortical bone. / Shin, Mihee; Zhang, Min; Vom Scheidt, Annika; Pelletier, Matthew H; Walsh, William R; Martens, Penny J; Kruzic, Jamie J; Busse, Björn; Gludovatz, Bernd.

In: J MECH BEHAV BIOMED, Vol. 129, 05.2022, p. 105155.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Shin, M, Zhang, M, Vom Scheidt, A, Pelletier, MH, Walsh, WR, Martens, PJ, Kruzic, JJ, Busse, B & Gludovatz, B 2022, 'Impact of test environment on the fracture resistance of cortical bone', J MECH BEHAV BIOMED, vol. 129, pp. 105155. https://doi.org/10.1016/j.jmbbm.2022.105155

APA

Shin, M., Zhang, M., Vom Scheidt, A., Pelletier, M. H., Walsh, W. R., Martens, P. J., Kruzic, J. J., Busse, B., & Gludovatz, B. (2022). Impact of test environment on the fracture resistance of cortical bone. J MECH BEHAV BIOMED, 129, 105155. https://doi.org/10.1016/j.jmbbm.2022.105155

Vancouver

Shin M, Zhang M, Vom Scheidt A, Pelletier MH, Walsh WR, Martens PJ et al. Impact of test environment on the fracture resistance of cortical bone. J MECH BEHAV BIOMED. 2022 May;129:105155. https://doi.org/10.1016/j.jmbbm.2022.105155

Bibtex

@article{52296bf142104ded82a7bec85b63588d,
title = "Impact of test environment on the fracture resistance of cortical bone",
abstract = "Water is a crucial component of bone, affecting the interplay of collagen and minerals and contributing to bone's high strength and ductility. Dehydration has been shown to significantly effect osseous mechanical properties; however, studies comparing the effects of various dehydrating environments on fracture toughness of bone are scarce. Accordingly, the crack resistance curve (R-curve) behavior of human and sheep cortical bone was characterized in a bio-bath, in ambient pressure air, and in scanning electron microscopes (SEMs) under three different environmental conditions (water vapor pressure, air pressure, and high-vacuum). The aim of this work was to better understand the impact of test environment on both intrinsic and extrinsic toughening and hence crack initiation toughness, K0 and crack growth resistance, dK/dΔa. Results show significantly lower K0 values for samples that were tested inside SEMs combined with pronounced extrinsic toughening through microcracking and crack path deflections out of the mode I plane. Importantly, all three SEM test environments gave similar results, and thus it does not matter which type of SEM is used. Ex situ testing of hydrated samples revealed similar K0 for both environments but elevated crack growth resistance for testing in ambient air relative to the bio-bath. Our data reveals the experimental difficulties to directly observe microscale crack propagation in cortical bone that resembles the in vivo situation. Ex situ testing immersed in Hanks' Balanced Salt Solution (HBSS) with subsequent crack path analysis, while tedious, is thought to presents the most realistic picture of the in vivo structure-fracture property relations in biological tissue.",
author = "Mihee Shin and Min Zhang and {Vom Scheidt}, Annika and Pelletier, {Matthew H} and Walsh, {William R} and Martens, {Penny J} and Kruzic, {Jamie J} and Bj{\"o}rn Busse and Bernd Gludovatz",
note = "Copyright {\textcopyright} 2022 Elsevier Ltd. All rights reserved.",
year = "2022",
month = may,
doi = "10.1016/j.jmbbm.2022.105155",
language = "English",
volume = "129",
pages = "105155",
journal = "J MECH BEHAV BIOMED",
issn = "1751-6161",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Impact of test environment on the fracture resistance of cortical bone

AU - Shin, Mihee

AU - Zhang, Min

AU - Vom Scheidt, Annika

AU - Pelletier, Matthew H

AU - Walsh, William R

AU - Martens, Penny J

AU - Kruzic, Jamie J

AU - Busse, Björn

AU - Gludovatz, Bernd

N1 - Copyright © 2022 Elsevier Ltd. All rights reserved.

PY - 2022/5

Y1 - 2022/5

N2 - Water is a crucial component of bone, affecting the interplay of collagen and minerals and contributing to bone's high strength and ductility. Dehydration has been shown to significantly effect osseous mechanical properties; however, studies comparing the effects of various dehydrating environments on fracture toughness of bone are scarce. Accordingly, the crack resistance curve (R-curve) behavior of human and sheep cortical bone was characterized in a bio-bath, in ambient pressure air, and in scanning electron microscopes (SEMs) under three different environmental conditions (water vapor pressure, air pressure, and high-vacuum). The aim of this work was to better understand the impact of test environment on both intrinsic and extrinsic toughening and hence crack initiation toughness, K0 and crack growth resistance, dK/dΔa. Results show significantly lower K0 values for samples that were tested inside SEMs combined with pronounced extrinsic toughening through microcracking and crack path deflections out of the mode I plane. Importantly, all three SEM test environments gave similar results, and thus it does not matter which type of SEM is used. Ex situ testing of hydrated samples revealed similar K0 for both environments but elevated crack growth resistance for testing in ambient air relative to the bio-bath. Our data reveals the experimental difficulties to directly observe microscale crack propagation in cortical bone that resembles the in vivo situation. Ex situ testing immersed in Hanks' Balanced Salt Solution (HBSS) with subsequent crack path analysis, while tedious, is thought to presents the most realistic picture of the in vivo structure-fracture property relations in biological tissue.

AB - Water is a crucial component of bone, affecting the interplay of collagen and minerals and contributing to bone's high strength and ductility. Dehydration has been shown to significantly effect osseous mechanical properties; however, studies comparing the effects of various dehydrating environments on fracture toughness of bone are scarce. Accordingly, the crack resistance curve (R-curve) behavior of human and sheep cortical bone was characterized in a bio-bath, in ambient pressure air, and in scanning electron microscopes (SEMs) under three different environmental conditions (water vapor pressure, air pressure, and high-vacuum). The aim of this work was to better understand the impact of test environment on both intrinsic and extrinsic toughening and hence crack initiation toughness, K0 and crack growth resistance, dK/dΔa. Results show significantly lower K0 values for samples that were tested inside SEMs combined with pronounced extrinsic toughening through microcracking and crack path deflections out of the mode I plane. Importantly, all three SEM test environments gave similar results, and thus it does not matter which type of SEM is used. Ex situ testing of hydrated samples revealed similar K0 for both environments but elevated crack growth resistance for testing in ambient air relative to the bio-bath. Our data reveals the experimental difficulties to directly observe microscale crack propagation in cortical bone that resembles the in vivo situation. Ex situ testing immersed in Hanks' Balanced Salt Solution (HBSS) with subsequent crack path analysis, while tedious, is thought to presents the most realistic picture of the in vivo structure-fracture property relations in biological tissue.

U2 - 10.1016/j.jmbbm.2022.105155

DO - 10.1016/j.jmbbm.2022.105155

M3 - SCORING: Journal article

C2 - 35313188

VL - 129

SP - 105155

JO - J MECH BEHAV BIOMED

JF - J MECH BEHAV BIOMED

SN - 1751-6161

ER -