Impact of smoking status on health-related quality of life (HRQoL) in cancer survivors

TY - JOUR

T1 - Impact of smoking status on health-related quality of life (HRQoL) in cancer survivors

AU - Nolazco, José Ignacio

AU - Rosner, Bernard A

AU - Roebuck, Emily H

AU - Bergerot, Cristiane Decat

AU - Rammant, Elke

AU - Iyer, Geetha S

AU - Tang, Yuzhe

AU - Al-Faouri, Ra'ad

AU - Filipas, Dejan K

AU - Leapman, Michael S

AU - Mossanen, Matthew

AU - Chang, Steven Lee

N1 - Copyright © 2024 Nolazco, Rosner, Roebuck, Bergerot, Rammant, Iyer, Tang, Al-Faouri, Filipas, Leapman, Mossanen and Chang.

PY - 2023

Y1 - 2023

N2 - INTRODUCTION: The Health-Related Quality of Life (HRQoL) often declines among cancer survivors due to many factors. Some cancer patients who smoke before the cancer diagnosis continue this harmful habit, potentially contributing to a more significant decline in their HRQoL. Therefore, this study investigates the association between smoking status and HRQoL in cancer survivors.METHODS: We conducted a cross-sectional study utilizing self-reported cancer history from 39,578 participants of the Behavioral Risk Factor Surveillance System (BRFSS) database, leveraging 2016 and 2020 year questionaries. A multidimensional composite outcome was created to assess HRQoL, integrating four distinct dimensions - general health, mental health, physical health, and activity limitations. After accounting for the complex survey design, logistic regression models were used to analyze the association between smoking status and poor HRQoL, adjusting for demographic, socioeconomic, and health-related confounders.RESULTS: Our study found that, after adjusting for potential confounders, current smokers exhibited a significantly poorer HRQoL than never smokers (OR 1.65, 95%CI 1.40-1.93). Furthermore, former smokers showed a poorer HRQoL than never smokers; however, this association was not as strong as current smokers (OR 1.22, 95%CI 1.09-1.38).CONCLUSION: Our findings highlight the adverse association of smoking with poor HRQoL in cancer survivors, underscoring the importance of healthcare professionals prioritizing smoking cessation and providing tailored interventions to support this goal.

AB - INTRODUCTION: The Health-Related Quality of Life (HRQoL) often declines among cancer survivors due to many factors. Some cancer patients who smoke before the cancer diagnosis continue this harmful habit, potentially contributing to a more significant decline in their HRQoL. Therefore, this study investigates the association between smoking status and HRQoL in cancer survivors.METHODS: We conducted a cross-sectional study utilizing self-reported cancer history from 39,578 participants of the Behavioral Risk Factor Surveillance System (BRFSS) database, leveraging 2016 and 2020 year questionaries. A multidimensional composite outcome was created to assess HRQoL, integrating four distinct dimensions - general health, mental health, physical health, and activity limitations. After accounting for the complex survey design, logistic regression models were used to analyze the association between smoking status and poor HRQoL, adjusting for demographic, socioeconomic, and health-related confounders.RESULTS: Our study found that, after adjusting for potential confounders, current smokers exhibited a significantly poorer HRQoL than never smokers (OR 1.65, 95%CI 1.40-1.93). Furthermore, former smokers showed a poorer HRQoL than never smokers; however, this association was not as strong as current smokers (OR 1.22, 95%CI 1.09-1.38).CONCLUSION: Our findings highlight the adverse association of smoking with poor HRQoL in cancer survivors, underscoring the importance of healthcare professionals prioritizing smoking cessation and providing tailored interventions to support this goal.

U2 - 10.3389/fonc.2023.1261041

DO - 10.3389/fonc.2023.1261041

M3 - SCORING: Journal article

C2 - 38239633

VL - 13

SP - 1261041

JO - FRONT ONCOL

JF - FRONT ONCOL

SN - 2234-943X

ER -