Identification of cis-acting elements as DNase I hypersensitive sites in lysozyme gene chromatin

  • A E Sippel
  • H Saueressig
  • M C Huber
  • H C Hoefer
  • A Stief
  • U Borgmeyer
  • C Bonifer

Abstract

DNase I hypersensitive sites in chromatin of eukaryotic cells mark the positions of multifactorial cis-acting elements. Mapping DH sites by indirect end labeling is a convenient procedure used for identifying regulatory elements within extensive regions of chromatin and for gaining information about their functional specificity as well as their fine structure.

Bibliographical data

Original languageEnglish
ISSN0076-6879
Publication statusPublished - 1996
PubMed 8902808