Identification of cis-acting elements as DNase I hypersensitive sites in lysozyme gene chromatin
Beteiligte Einrichtungen
Abstract
DNase I hypersensitive sites in chromatin of eukaryotic cells mark the positions of multifactorial cis-acting elements. Mapping DH sites by indirect end labeling is a convenient procedure used for identifying regulatory elements within extensive regions of chromatin and for gaining information about their functional specificity as well as their fine structure.