Research ExplorerPublicationsHuman erythrocyte fragmentation during ex-vivo pig organ per...

Human erythrocyte fragmentation during ex-vivo pig organ perfusion

Standard

Human erythrocyte fragmentation during ex-vivo pig organ perfusion. / Habibabady, Zahra; Sendil, Selin; Ellett, Felix; Pollok, Franziska; Elias, Gabriela ; French, Beth; Sun, Wenji; Braileanu, Gheorghe; Burdorf, Lars; Irimia, Daniel; Pierson, Richard N; Azimzadeh, Agnes.

In: XENOTRANSPLANTATION, Vol. 29, No. 2, e12729, 29.03.2022, p. e12729.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Habibabady, Z, Sendil, S, Ellett, F, Pollok, F, Elias, G, French, B, Sun, W, Braileanu, G, Burdorf, L, Irimia, D, Pierson, RN & Azimzadeh, A 2022, 'Human erythrocyte fragmentation during ex-vivo pig organ perfusion', XENOTRANSPLANTATION, vol. 29, no. 2, e12729, pp. e12729. https://doi.org/10.1111/xen.12729

APA

Habibabady, Z., Sendil, S., Ellett, F., Pollok, F., Elias, G., French, B., Sun, W., Braileanu, G., Burdorf, L., Irimia, D., Pierson, R. N., & Azimzadeh, A. (2022). Human erythrocyte fragmentation during ex-vivo pig organ perfusion. XENOTRANSPLANTATION, 29(2), e12729. [e12729]. https://doi.org/10.1111/xen.12729

Vancouver

Habibabady Z, Sendil S, Ellett F, Pollok F, Elias G, French B et al. Human erythrocyte fragmentation during ex-vivo pig organ perfusion. XENOTRANSPLANTATION. 2022 Mar 29;29(2):e12729. e12729. https://doi.org/10.1111/xen.12729

Bibtex

@article{7f8fa5985ba84293875bb5d516d8853e,
title = "Human erythrocyte fragmentation during ex-vivo pig organ perfusion",
abstract = "Platelet sequestration is a common process during organ reperfusion after transplantation. However, instead of lower platelet counts, when using traditional hemocytometers and light microscopy, we observed physiologically implausible platelet counts in the course of ex-vivo lung and liver xenograft organ perfusion studies. We employed conventional flow cytometry (FC) and imaging FC (AMINS ImageStream X) to investigate the findings and found platelet-sized fragments in the circulation that are mainly derived from red blood cell membranes. We speculate that this erythrocyte fragmentation contributes to anemia during in-vivo organ xenotransplant.",
author = "Zahra Habibabady and Selin Sendil and Felix Ellett and Franziska Pollok and Gabriela Elias and Beth French and Wenji Sun and Gheorghe Braileanu and Lars Burdorf and Daniel Irimia and Pierson, {Richard N} and Agnes Azimzadeh",
year = "2022",
month = mar,
day = "29",
doi = "10.1111/xen.12729",
language = "English",
volume = "29",
pages = "e12729",
journal = "XENOTRANSPLANTATION",
issn = "0908-665X",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Human erythrocyte fragmentation during ex-vivo pig organ perfusion

AU - Habibabady, Zahra

AU - Sendil, Selin

AU - Ellett, Felix

AU - Pollok, Franziska

AU - Elias, Gabriela

AU - French, Beth

AU - Sun, Wenji

AU - Braileanu, Gheorghe

AU - Burdorf, Lars

AU - Irimia, Daniel

AU - Pierson, Richard N

AU - Azimzadeh, Agnes

PY - 2022/3/29

Y1 - 2022/3/29

N2 - Platelet sequestration is a common process during organ reperfusion after transplantation. However, instead of lower platelet counts, when using traditional hemocytometers and light microscopy, we observed physiologically implausible platelet counts in the course of ex-vivo lung and liver xenograft organ perfusion studies. We employed conventional flow cytometry (FC) and imaging FC (AMINS ImageStream X) to investigate the findings and found platelet-sized fragments in the circulation that are mainly derived from red blood cell membranes. We speculate that this erythrocyte fragmentation contributes to anemia during in-vivo organ xenotransplant.

AB - Platelet sequestration is a common process during organ reperfusion after transplantation. However, instead of lower platelet counts, when using traditional hemocytometers and light microscopy, we observed physiologically implausible platelet counts in the course of ex-vivo lung and liver xenograft organ perfusion studies. We employed conventional flow cytometry (FC) and imaging FC (AMINS ImageStream X) to investigate the findings and found platelet-sized fragments in the circulation that are mainly derived from red blood cell membranes. We speculate that this erythrocyte fragmentation contributes to anemia during in-vivo organ xenotransplant.

U2 - 10.1111/xen.12729

DO - 10.1111/xen.12729

M3 - SCORING: Journal article

C2 - 35112383

VL - 29

SP - e12729

JO - XENOTRANSPLANTATION

JF - XENOTRANSPLANTATION

SN - 0908-665X

IS - 2

M1 - e12729

ER -