Histology and Serum Cytokine Responses in an Imported Infection, Germany

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Histology and Serum Cytokine Responses in an Imported Infection, Germany. / Tappe, Dennis; Booken, Nina; Böer-Auer, Almut; Rauch, Jessica; Schmiedel, Stefan; Reich, Kristian.

In: AM J TROP MED HYG, Vol. 98, No. 1, 01.2018, p. 248-251.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{352cdbe746664cf59eb772c439372c51,
title = "Histology and Serum Cytokine Responses in an Imported Infection, Germany",
abstract = "Rickettsia slovaca, a spotted fever group rickettsial pathogen, causes a syndrome consisting of scalp eschar and neck lymphadenopathy following tick bite. We analyzed the histologic skin reaction in the eschar, showing a prominent eosinophilic infiltration, as well as the presence of B lymphocytes and CD4- and CD8-positive T cells. Examination of the serum cytokine responses over time demonstrated an initial proinflammatory cytokine elevation followed by normalization.",
keywords = "Cytokines, Female, France, Germany, Humans, Lymphadenopathy, Middle Aged, Rickettsia, Scalp, Skin, Spotted Fever Group Rickettsiosis, Travel, Journal Article",
author = "Dennis Tappe and Nina Booken and Almut B{\"o}er-Auer and Jessica Rauch and Stefan Schmiedel and Kristian Reich",
year = "2018",
month = jan,
doi = "10.4269/ajtmh.17-0392",
language = "English",
volume = "98",
pages = "248--251",
journal = "AM J TROP MED HYG",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "1",

}

RIS

TY - JOUR

T1 - Histology and Serum Cytokine Responses in an Imported Infection, Germany

AU - Tappe, Dennis

AU - Booken, Nina

AU - Böer-Auer, Almut

AU - Rauch, Jessica

AU - Schmiedel, Stefan

AU - Reich, Kristian

PY - 2018/1

Y1 - 2018/1

N2 - Rickettsia slovaca, a spotted fever group rickettsial pathogen, causes a syndrome consisting of scalp eschar and neck lymphadenopathy following tick bite. We analyzed the histologic skin reaction in the eschar, showing a prominent eosinophilic infiltration, as well as the presence of B lymphocytes and CD4- and CD8-positive T cells. Examination of the serum cytokine responses over time demonstrated an initial proinflammatory cytokine elevation followed by normalization.

AB - Rickettsia slovaca, a spotted fever group rickettsial pathogen, causes a syndrome consisting of scalp eschar and neck lymphadenopathy following tick bite. We analyzed the histologic skin reaction in the eschar, showing a prominent eosinophilic infiltration, as well as the presence of B lymphocytes and CD4- and CD8-positive T cells. Examination of the serum cytokine responses over time demonstrated an initial proinflammatory cytokine elevation followed by normalization.

KW - Cytokines

KW - Female

KW - France

KW - Germany

KW - Humans

KW - Lymphadenopathy

KW - Middle Aged

KW - Rickettsia

KW - Scalp

KW - Skin

KW - Spotted Fever Group Rickettsiosis

KW - Travel

KW - Journal Article

U2 - 10.4269/ajtmh.17-0392

DO - 10.4269/ajtmh.17-0392

M3 - SCORING: Journal article

C2 - 29141745

VL - 98

SP - 248

EP - 251

JO - AM J TROP MED HYG

JF - AM J TROP MED HYG

SN - 0002-9637

IS - 1

ER -