Histology and Serum Cytokine Responses in an Imported Infection, Germany
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Abstract
Rickettsia slovaca, a spotted fever group rickettsial pathogen, causes a syndrome consisting of scalp eschar and neck lymphadenopathy following tick bite. We analyzed the histologic skin reaction in the eschar, showing a prominent eosinophilic infiltration, as well as the presence of B lymphocytes and CD4- and CD8-positive T cells. Examination of the serum cytokine responses over time demonstrated an initial proinflammatory cytokine elevation followed by normalization.
Bibliographical data
Original language | English |
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ISSN | 0002-9637 |
DOIs | |
Publication status | Published - 01.2018 |
PubMed | 29141745 |
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