Geschlechtsunterschiede bei Infektionserkrankungen

Claudia Beisel; Jan Lunzen; Ansgar W Lohse; Marylyn Martina Addo; Marcus Altfeld

doi:10.1055/s-0041-104246

Geschlechtsunterschiede bei Infektionserkrankungen

Standard

Geschlechtsunterschiede bei Infektionserkrankungen. / Beisel, Claudia; Lunzen, Jan; Lohse, Ansgar W ; Addo, Marylyn Martina; Altfeld, Marcus.

In: DEUT MED WOCHENSCHR, Vol. 140, No. 18, 09.2015, p. 1385-90.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Beisel, C, Lunzen, J, Lohse, AW , Addo, MM & Altfeld, M 2015, 'Geschlechtsunterschiede bei Infektionserkrankungen', DEUT MED WOCHENSCHR, vol. 140, no. 18, pp. 1385-90. https://doi.org/10.1055/s-0041-104246

APA

Beisel, C., Lunzen, J., Lohse, A. W., Addo, M. M., & Altfeld, M. (2015). Geschlechtsunterschiede bei Infektionserkrankungen. DEUT MED WOCHENSCHR, 140(18), 1385-90. https://doi.org/10.1055/s-0041-104246

Vancouver

Beisel C, Lunzen J, Lohse AW , Addo MM, Altfeld M. Geschlechtsunterschiede bei Infektionserkrankungen. DEUT MED WOCHENSCHR. 2015 Sep;140(18):1385-90. https://doi.org/10.1055/s-0041-104246

Bibtex

@article{9032d251d1d449a998dc45933f150af9,

title = "Geschlechtsunterschiede bei Infektionserkrankungen",

abstract = "Differences between women and men range from their anatomy, their natural social behavior to their susceptibility and response to different pathologies, including infectious diseases.The underlying mechanisms of sex differences in infectious diseases are manifold, including differences in exposure to common pathogens, genetic factors that modulate immune responses against pathogens and hormonal factors that may alter susceptibility or disease progression, and responsiveness to treatment. On one hand, these mechanisms lead to higher innate and adaptive immune responses in females, which result in faster clearance of acute infections and higher antibody responses to several vaccines, on the other hand this contributes to an increased susceptibility to chronic inflammatory diseases.In this review we summarize the underlying causes of sex differences in prevalence, clinical course of disease and treatment outcome of infectious diseases. In order to develop individualized treatment concepts, a fair balance between the sexes should be maintained in basic science, preclinical and clinical studies.",

author = "Claudia Beisel and Jan Lunzen and Lohse, {Ansgar W} and Addo, {Marylyn Martina} and Marcus Altfeld",

note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",

year = "2015",

month = sep,

doi = "10.1055/s-0041-104246",

language = "Deutsch",

volume = "140",

pages = "1385--90",

journal = "DEUT MED WOCHENSCHR",

issn = "0012-0472",

publisher = "Georg Thieme Verlag KG",

number = "18",

}

RIS

TY - JOUR

T1 - Geschlechtsunterschiede bei Infektionserkrankungen

AU - Beisel, Claudia

AU - Lunzen, Jan

AU - Lohse, Ansgar W

AU - Addo, Marylyn Martina

AU - Altfeld, Marcus

PY - 2015/9

Y1 - 2015/9

N2 - Differences between women and men range from their anatomy, their natural social behavior to their susceptibility and response to different pathologies, including infectious diseases.The underlying mechanisms of sex differences in infectious diseases are manifold, including differences in exposure to common pathogens, genetic factors that modulate immune responses against pathogens and hormonal factors that may alter susceptibility or disease progression, and responsiveness to treatment. On one hand, these mechanisms lead to higher innate and adaptive immune responses in females, which result in faster clearance of acute infections and higher antibody responses to several vaccines, on the other hand this contributes to an increased susceptibility to chronic inflammatory diseases.In this review we summarize the underlying causes of sex differences in prevalence, clinical course of disease and treatment outcome of infectious diseases. In order to develop individualized treatment concepts, a fair balance between the sexes should be maintained in basic science, preclinical and clinical studies.

AB - Differences between women and men range from their anatomy, their natural social behavior to their susceptibility and response to different pathologies, including infectious diseases.The underlying mechanisms of sex differences in infectious diseases are manifold, including differences in exposure to common pathogens, genetic factors that modulate immune responses against pathogens and hormonal factors that may alter susceptibility or disease progression, and responsiveness to treatment. On one hand, these mechanisms lead to higher innate and adaptive immune responses in females, which result in faster clearance of acute infections and higher antibody responses to several vaccines, on the other hand this contributes to an increased susceptibility to chronic inflammatory diseases.In this review we summarize the underlying causes of sex differences in prevalence, clinical course of disease and treatment outcome of infectious diseases. In order to develop individualized treatment concepts, a fair balance between the sexes should be maintained in basic science, preclinical and clinical studies.

U2 - 10.1055/s-0041-104246

DO - 10.1055/s-0041-104246

M3 - SCORING: Zeitschriftenaufsatz

C2 - 26360954

VL - 140

SP - 1385

EP - 1390

JO - DEUT MED WOCHENSCHR

JF - DEUT MED WOCHENSCHR

SN - 0012-0472

IS - 18

ER -