Genome-wide association analysis identifies susceptibility loci for migraine without aura.
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Genome-wide association analysis identifies susceptibility loci for migraine without aura. / Freilinger, Tobias; Anttila, Verneri; de Vries, Boukje; Malik, Rainer; Kallela, Mikko; Terwindt, Gisela M; Pozo-Rosich, Patricia; Winsvold, Bendik; Nyholt, Dale R; Oosterhout, van; Willebrordus, P J; Artto, Ville; Todt, Unda; Hämäläinen, Eija; Fernández-Morales, Jèssica; Louter, Mark A; Kaunisto, Mari A; Schoenen, Jean; Raitakari, Olli; Lehtimäki, Terho; Vila-Pueyo, Marta; Göbel, Hartmut; Wichmann, Erich; Sintas, Cèlia; Uitterlinden, Andre G; Hofman, Albert; Rivadeneira, Fernando; Heinze, Axel; Tronvik, Erling; Duijn, van; Cornelia, M; Kaprio, Jaakko; Cormand, Bru; Wessman, Maija; Frants, Rune R; Meitinger, Thomas; Müller-Myhsok, Bertram; Zwart, John-Anker; Färkkilä, Markus; Kubisch, Christian; Ferrari, Michel D; Palotie, Aarno; Dichgans, Martin; Maagdenberg, van den; Arn, M J M; Consortium, International Headache Genetics.
In: NAT GENET, Vol. 44, No. 7, 7, 2012, p. 777-782.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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T1 - Genome-wide association analysis identifies susceptibility loci for migraine without aura.
AU - Freilinger, Tobias
AU - Anttila, Verneri
AU - de Vries, Boukje
AU - Malik, Rainer
AU - Kallela, Mikko
AU - Terwindt, Gisela M
AU - Pozo-Rosich, Patricia
AU - Winsvold, Bendik
AU - Nyholt, Dale R
AU - Oosterhout, van
AU - Willebrordus, P J
AU - Artto, Ville
AU - Todt, Unda
AU - Hämäläinen, Eija
AU - Fernández-Morales, Jèssica
AU - Louter, Mark A
AU - Kaunisto, Mari A
AU - Schoenen, Jean
AU - Raitakari, Olli
AU - Lehtimäki, Terho
AU - Vila-Pueyo, Marta
AU - Göbel, Hartmut
AU - Wichmann, Erich
AU - Sintas, Cèlia
AU - Uitterlinden, Andre G
AU - Hofman, Albert
AU - Rivadeneira, Fernando
AU - Heinze, Axel
AU - Tronvik, Erling
AU - Duijn, van
AU - Cornelia, M
AU - Kaprio, Jaakko
AU - Cormand, Bru
AU - Wessman, Maija
AU - Frants, Rune R
AU - Meitinger, Thomas
AU - Müller-Myhsok, Bertram
AU - Zwart, John-Anker
AU - Färkkilä, Markus
AU - Kubisch, Christian
AU - Ferrari, Michel D
AU - Palotie, Aarno
AU - Dichgans, Martin
AU - Maagdenberg, van den
AU - Arn, M J M
AU - Consortium, International Headache Genetics
PY - 2012
Y1 - 2012
N2 - Migraine without aura is the most common form of migraine, characterized by recurrent disabling headache and associated autonomic symptoms. To identify common genetic variants associated with this migraine type, we analyzed genome-wide association data of 2,326 clinic-based German and Dutch individuals with migraine without aura and 4,580 population-matched controls. We selected SNPs from 12 loci with 2 or more SNPs associated with P values of
AB - Migraine without aura is the most common form of migraine, characterized by recurrent disabling headache and associated autonomic symptoms. To identify common genetic variants associated with this migraine type, we analyzed genome-wide association data of 2,326 clinic-based German and Dutch individuals with migraine without aura and 4,580 population-matched controls. We selected SNPs from 12 loci with 2 or more SNPs associated with P values of
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Genetic Predisposition to Disease
KW - Polymorphism, Single Nucleotide
KW - Case-Control Studies
KW - Genetic Loci
KW - Genome-Wide Association Study/methods
KW - Microfilament Proteins/genetics
KW - Low Density Lipoprotein Receptor-Related Protein-1/genetics
KW - MADS Domain Proteins/genetics
KW - Migraine without Aura/genetics
KW - Myogenic Regulatory Factors/genetics
KW - Protein-Serine-Threonine Kinases/genetics
KW - Receptors, Transforming Growth Factor beta/genetics
KW - TRPM Cation Channels/genetics
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Genetic Predisposition to Disease
KW - Polymorphism, Single Nucleotide
KW - Case-Control Studies
KW - Genetic Loci
KW - Genome-Wide Association Study/methods
KW - Microfilament Proteins/genetics
KW - Low Density Lipoprotein Receptor-Related Protein-1/genetics
KW - MADS Domain Proteins/genetics
KW - Migraine without Aura/genetics
KW - Myogenic Regulatory Factors/genetics
KW - Protein-Serine-Threonine Kinases/genetics
KW - Receptors, Transforming Growth Factor beta/genetics
KW - TRPM Cation Channels/genetics
M3 - SCORING: Journal article
VL - 44
SP - 777
EP - 782
JO - NAT GENET
JF - NAT GENET
SN - 1061-4036
IS - 7
M1 - 7
ER -