Genome-wide association analysis identifies susceptibility loci for migraine without aura.

  • Tobias Freilinger
  • Verneri Anttila
  • Boukje de Vries
  • Rainer Malik
  • Mikko Kallela
  • Gisela M Terwindt
  • Patricia Pozo-Rosich
  • Bendik Winsvold
  • Dale R Nyholt
  • van Oosterhout
  • P J Willebrordus
  • Ville Artto
  • Unda Todt
  • Eija Hämäläinen
  • Jèssica Fernández-Morales
  • Mark A Louter
  • Mari A Kaunisto
  • Jean Schoenen
  • Olli Raitakari
  • Terho Lehtimäki
  • Marta Vila-Pueyo
  • Hartmut Göbel
  • Erich Wichmann
  • Cèlia Sintas
  • Andre G Uitterlinden
  • Albert Hofman
  • Fernando Rivadeneira
  • Axel Heinze
  • Erling Tronvik
  • van Duijn
  • M Cornelia
  • Jaakko Kaprio
  • Bru Cormand
  • Maija Wessman
  • Rune R Frants
  • Thomas Meitinger
  • Bertram Müller-Myhsok
  • John-Anker Zwart
  • Markus Färkkilä
  • Christian Kubisch
  • Michel D Ferrari
  • Aarno Palotie
  • Martin Dichgans
  • van den Maagdenberg
  • M J M Arn
  • International Headache Genetics Consortium

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Abstract

Migraine without aura is the most common form of migraine, characterized by recurrent disabling headache and associated autonomic symptoms. To identify common genetic variants associated with this migraine type, we analyzed genome-wide association data of 2,326 clinic-based German and Dutch individuals with migraine without aura and 4,580 population-matched controls. We selected SNPs from 12 loci with 2 or more SNPs associated with P values of

Bibliographical data

Original languageEnglish
Article number7
ISSN1061-4036
Publication statusPublished - 2012
pubmed 22683712