Formation of COPI-coated vesicles at a glance

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Formation of COPI-coated vesicles at a glance. / Arakel, Eric C; Schwappach, Blanche.

In: J CELL SCI, Vol. 131, No. 5, 13.03.2018.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{029fb3c8e198422dab095297775804c1,
title = "Formation of COPI-coated vesicles at a glance",
abstract = "The coat protein complex I (COPI) allows the precise sorting of lipids and proteins between Golgi cisternae and retrieval from the Golgi to the ER. This essential role maintains the identity of the early secretory pathway and impinges on key cellular processes, such as protein quality control. In this Cell Science at a Glance and accompanying poster, we illustrate the different stages of COPI-coated vesicle formation and revisit decades of research in the context of recent advances in the elucidation of COPI coat structure. By calling attention to an array of questions that have remained unresolved, this review attempts to refocus the perspectives of the field.",
keywords = "Animals, COP-Coated Vesicles/genetics, Coat Protein Complex I/genetics, Endoplasmic Reticulum/genetics, Golgi Apparatus/genetics, Humans, Protein Transport/genetics",
author = "Arakel, {Eric C} and Blanche Schwappach",
note = "{\textcopyright} 2018. Published by The Company of Biologists Ltd.",
year = "2018",
month = mar,
day = "13",
doi = "10.1242/jcs.209890",
language = "English",
volume = "131",
journal = "J CELL SCI",
issn = "0021-9533",
publisher = "Company of Biologists Ltd",
number = "5",

}

RIS

TY - JOUR

T1 - Formation of COPI-coated vesicles at a glance

AU - Arakel, Eric C

AU - Schwappach, Blanche

N1 - © 2018. Published by The Company of Biologists Ltd.

PY - 2018/3/13

Y1 - 2018/3/13

N2 - The coat protein complex I (COPI) allows the precise sorting of lipids and proteins between Golgi cisternae and retrieval from the Golgi to the ER. This essential role maintains the identity of the early secretory pathway and impinges on key cellular processes, such as protein quality control. In this Cell Science at a Glance and accompanying poster, we illustrate the different stages of COPI-coated vesicle formation and revisit decades of research in the context of recent advances in the elucidation of COPI coat structure. By calling attention to an array of questions that have remained unresolved, this review attempts to refocus the perspectives of the field.

AB - The coat protein complex I (COPI) allows the precise sorting of lipids and proteins between Golgi cisternae and retrieval from the Golgi to the ER. This essential role maintains the identity of the early secretory pathway and impinges on key cellular processes, such as protein quality control. In this Cell Science at a Glance and accompanying poster, we illustrate the different stages of COPI-coated vesicle formation and revisit decades of research in the context of recent advances in the elucidation of COPI coat structure. By calling attention to an array of questions that have remained unresolved, this review attempts to refocus the perspectives of the field.

KW - Animals

KW - COP-Coated Vesicles/genetics

KW - Coat Protein Complex I/genetics

KW - Endoplasmic Reticulum/genetics

KW - Golgi Apparatus/genetics

KW - Humans

KW - Protein Transport/genetics

U2 - 10.1242/jcs.209890

DO - 10.1242/jcs.209890

M3 - SCORING: Review article

C2 - 29535154

VL - 131

JO - J CELL SCI

JF - J CELL SCI

SN - 0021-9533

IS - 5

ER -